University of Dundee

Technologist / Scientific Officer (Proteomics and Mass Spectrometry)

Unit: 
Centre for Advanced Scientific Technologies
Job Reference: 
SLSC0548
Closing Date: 
Wednesday, March 27, 2019
Salary: 
Grade 6 (£26,243 - £32,236) or Grade 7 (£32,236 - £39,609) depending on experience

FingerPrints Proteomics Facility

Grade 6 (£26,243 - £32,236) or Grade 7 (£32,236 - £39,609) depending on experience

Applications are invited for the position of Technologist / Scientific Officer within the FingerPrints Proteomics Facility based in the Discovery Centre, School of Life Sciences, University of Dundee. We would welcome applications from current active researchers and from those who have taken a career break. The successful applicant will work as part of a small yet dynamic team to support existing facility operations, services, and on-going proteomics and mass spectrometry based projects.

The facility offers a wide range of proteomic and mass spectrometry based services that include protein identification, protein characterisation (e.g. phosphorylation) and protein quantitation (e.g. SILAC, TMT, LFQ and SRM/MRM). The facility has 7 full time staff members that include a facility manager, 2 Senior Scientific Officers and 4 Research Technicians. It is extremely well equipped with a wide range of mass spectrometry systems, including  2 Orbitrap Fusions, Q-Exactive HF-X, Q-Exactive HF, 7 Q-Exactive Plus, 4 LTQ Orbitrap Velos Pro, TSQ Quantiva, LTQ Velos, Agilent 6520 Q-TOF and a Bruker Autoflex Speed MALDI-TOF.

This is an excellent opportunity for a technically minded individual who enjoys working in a lab environment with instrumentation and has a consistent logical approach to problem solving. It is expected that the successful candidate will have practical knowledge and experience of working in a similar environment, and should have the following qualities: a team player, results orientated with excellent attention to detail, good computer literacy skills with a strong focus on customer service. 

Duties to include: dealing with sample submission requests, preparation of samples for MS analysis, setting up and operation of MS systems including cleaning, tuning and calibration, troubleshooting and basic maintenance of MS and UHPLC systems and analysis of MS data from qualitative and quantitative studies.

Knowledge and/or experience of the following techniques and instrumentation would be an distinct advantage: processing of low abundance protein samples, in-solution/in-gel digestion, protein/peptide quantitation, SDS-PAGE, processing and analysis of samples for large scale quantitative studies (SILAC/TMT and LFQ), phosphopeptide mapping, peptide fractionation (High pH RP), MALDI-TOF, nLC-MS/MS, Q-TOF, Q-IT and LTQ-FT. Knowledge and experience in the use of proteomics software for instrument control and data analysis such as Xcalibur, Chromeleon, Mascot, Proteome Discoverer, MaxQuant, Progenesis QI, Scaffold and Peaks would also be a distinct advantage as would experience with quality control (QC). If you think you have the necessary qualities and experience we are looking for then you are encouraged to apply.

There may be an opportunity to appoint candidates who have less experience or who do not fully meet the required criteria for the Grade 7 position to a Grade 6 role within the facility.

The position is available immediately for 12 months in the first instance. There will be potential to renew based on continued funding.

Informal enquires should be directed to the facility manager (Douglas Lamont), Tel: (01382) 388275, or e-mail d.j.lamont@dundee.ac.uk.

We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.

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The diversity of our staff and students helps to make the University of Dundee one of the top universities in the UK. Family friendly policies, staff support networks for BME and LGBT staff, membership of Athena SWAN and Stonewall, as well a full range of disability services, create an enjoyable and inclusive place to work.