University of Dundee

Postdoctoral Research Assistant

Unit: 
Medical Research Council Protein Phosphorylation and Ubiquitylation Unit
Job Reference: 
SLSC0231
Closing Date: 
Friday, March 31, 2017
Salary: 
Grade 7, Scale Points 29 - 31 only (£31,076- £ 32,958 per annum)

Applications are invited for a post-doctoral position to work with Prof John Rouse aimed at apply proteomic approaches to study novel protein kinases that control genome stability and which represent potential anti-cancer drug targets.

We seek a talented and enthusiastic post-doctoral scientist who will be based at the University of Dundee with a background in mass spectrometry and proteomics but with the desire to biology studies as well. Applicants should have a PhD in a relevant scientific discipline, such as biochemistry or similar, a good academic track record and have published at least one first authored paper in an international journal. The candidate will ideally have experience with large-scale proteome and/or phosphoproteome analyses, and knowledge and working experience with mass spectrometry systems and quantitative proteomics as well as the ability to apply bioinformatic tools to analyse large-scale data. Experience with Tandem Mass Tag (TMT) labelling is desirable, and knowledge of cell signalling, cancer and cell biology would be an advantage, but is not essential. In addition, the candidate should be able to work independently and thrive in a multi-disciplinary research environment. Strong interpersonal and communication skills are essential as is the ability to work as part of a team.

The position is available for 2 years with the possibility of further 2 year extension.

The position will be on the University of Dundee Grade 7 scale points 29-31 only (£31,076–£32,958 per annum).

Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment will be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 28, £30,175).

For informal enquiries please contact Professor John Rouse j.rouse@dundee.ac.uk

MRC Protein Phosphorylation and Ubiquitylation Unit (PPU):

The MRC-PPU and the one of the world’s most renowned centres for research on protein phosphorylation and ubiquitylation (http://www.ppu.mrc.ac.uk/). Many world leading researchers in the field of signal transduction have trained within the MRC-PPU. The major aims of the MRC-PPU are to advance understanding of the role of protein phosphorylation and ubiquitylation in cell regulation and human disease, to facilitate the development of drugs to treat diseases caused by abnormalities in phosphorylation, to generate reagents and improve technologies. A key remit of the MRC-PPU is to train the next generation of scientists who will advance our understanding in this crucial area of medical research. The Unit facility is equipped with eight state-of-the art-mass spectrometers, which include three Orbitraps (one Fusion, two Velos Pro), a Velos Pro ETD, a QTrap5500 and UltrafleXtreme and RapiFlex MALDI TOF mass spectrometers. Please consult the Unit website for further details of its research programmes (http://www.ppu.mrc.ac.uk).

School of Life Sciences:

School of Life Sciences at the University of Dundee is the highest-rated for Biological Sciences in the UK by the main standard of University research performance REF2014 (http://www.lifesci.dundee.ac.uk/). Comprising about 100 research groups, the highest number of citations-per-paper for biological sciences in Europe (2013 and 2014 QS World University Rankings), over £100 million of research income in 2013 and nearly 900 staff from over 60 countries worldwide, the School enjoys a reputation as one of the most dynamic international centres for molecular cell biology, with outstanding laboratory and technology facilities. 'Lateral' and 'vertical' interactions within and between research groups are actively encouraged and 13% of publications in the past 5 years have been collaborations between two or more groups.

How to apply:

To apply on-line click here.

The University of Dundee is a diverse community and is committed to equality of opportunity for all by providing a supportive, flexible and inclusive working environment.  We have family friendly policies (including flexible working and childcare vouchers), staff groups for LGBT and BME; and prayer room facilities.

The University of Dundee has received the Athena SWAN Bronze Award (http://www.dundee.ac.uk/about/athenaswan/) which recognises the promotion of gender equality and has made further commitment to advancing inclusive culture which supports and encourages all under-represented groups.

The University of Dundee is a Scottish Registered Charity, No. SC015096.