Alan Prescott has been award 3rd Prize in the British Society of Cell Biology (BSCB) Image Competition 2017. His confocal image is of a transverse section of the rectus muscle of the eye taken from the mito-QC mouse (McWilliams et al., (2016) JCB, 214(3)). Mitochondria express eGFP and mCherry but in lysosomes the eGFP, green fluorescence is quenched. Bright red dots are mitolysosomes. Nuclei are DAPI blue.
Cell Signalling and Immunology
School of Life Sciences scientists have won a hat-trick of funding awards from the Wellcome Trust that will see more than £6million invested in their research. Professors Doreen Cantrell, Mark Field and Grahame Hardie have been successful in winning grants from Wellcome.
Dr Ignacio Moraga has been awarded €1.7 million to investigate the role that communication between cells plays in autoimmune diseases. The prestigious European Research Council (ERC) starting grant will fund his research over the next five years. Dr Moraga and his team are studying immune response action in the hope of designing better medicines for conditions such as lupus, arthritis and other debilitating autoimmune diseases.
Professor Sheng-Cai Lin, Dean of Life Sciences at Xiamen University, China gave the School of Life Science
Dr David McEwan, a principal investigator based in the division of Cell Signalling and Immunology, has been awarded a Tenovus Scotland grant for £100k. The grant will allow his group to study the cross talk between autophagy, infection and immunity.
nflammasomes are scaffolds that are assembled in the host cytosol to cope with pathogens and cellular stress. The pattern-recognition receptors NLRP1, NLRP3, NLRC4, AIM2 and Pyrin all assemble distinct inflammasome platforms that contribute to host defense through proteolytic maturation and secretion of the inflammatory cytokines interleukin-(IL)1β and IL18, and by inducing pyroptosis, a pro-inflammatory regulated cell death mode.
Stephen Fry has praised University of Dundee academics for their efforts in communicating their research to the public. Professor Jennifer Woof from the School named Engaged Researcher of the Year in recognition of her outstanding work with schools and the public to raise awareness of science.