University of Dundee

Cell Signalling and Immunology 2018

Ercoli G, Fernandes VE, Chung WY, Wanford JJ, Thomson S, Bayliss CD, Straatman K, Crocker PR, Dennison A, Martinez-Pomares L, Andrew PW, Moxon ER, Oggioni MR. 2018. Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia. Nature Microbiology. 3:600-610. Available from: 10.1038/s41564-018-0147-1

Fyffe FA, Hawley SA, Gray A, Hardie DG. 2018. Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK. Neumann D, Viollet B, editors. In AMPK : Methods and Protocols. Humana Press. pp. 69-86. (Methods in Molecular Biology). Available from: 10.1007/978-1-4939-7598-3_5

Hardie DG. 2018. Keeping the home fires burning: AMP-activated protein kinase. Journal of the Royal Society Interface. 15(138). Available from: 10.1098/rsif.2017.0774

Hawley SA, Fyffe FA, Russell FM, Gowans GJ, Hardie DG. 2018. Intact Cell Assays to Monitor AMPK and Determine the Contribution of the AMP-Binding or ADaM Sites to Activation. Neumann D, Viollet B, editors. In AMPK : Methods and Protocols. Humana Press. pp. 239-253. (Methods in Molecular Biology). Available from: 10.1007/978-1-4939-7598-3_16

Hoffmann T, Cwiklinski E, Shah D, Stretton C, Hyde R, Taylor P, Hundal H. 2018. Effects of sodium and amino acid substrate availability upon the expression and stability of the SNAT2 (SLC38A2) amino acid transporter. Frontiers in Pharmacology. 9:1-9. Available from: 10.3389/fphar.2018.00063

Lin S-C, Hardie D. 2018. AMPK: Sensing Glucose as well as Cellular Energy Status. Cell Metabolism. 27(2):299-313. Available from: 10.1016/j.cmet.2017.10.009

Loftus RM, Assmann N, Kedia-Mehta N, O'Brien KL, Garcia A, Gillespie C, Hukelmann JL, Oefner PJ, Lamond AI, Gardiner CM, Dettmer K, Cantrell DA, Sinclair LV, Finlay DK. 2018. Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice. Nature Communications. 9(1):1-15. Available from: 10.1038/s41467-018-04719-2

Lu H, Bogdanovic E, Yu Z, Cho C, Liu L, Ho K, Guo J, Yeung LSN, Lehmann R, Hundal HS, Giacca A, Fantus IG. 2018. Combined Hyperglycemia and Hyperinsulinemia-induced Insulin Resistance in Adipocytes is associated with Dual Signaling Defects mediated by PKC-ζ. Endocrinology. 159(4):1658-1677. Available from: 10.1210/en.2017-00312

Morgan EL, Wasson CW, Hanson L, Kealy D, Pentland I, McGuire V, Scarpini C, Coleman N, Arthur JSC, Parish JL, Roberts S, Macdonald A. 2018. STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle. PLoS Pathogens. 14(4):1-33. Available from: 10.1371/journal.ppat.1006975

Nagala M, McKenzie E, Richards H, Sharma R, Thomson S, Mastroeni P, Crocker P. 2018. Expression of Siglec-E alters the phenotype of macrophages but does not affect LPS-driven cytokine production or TLR4 endocytosis. Frontiers in Immunology. 8:1-17. Available from: 10.3389/fimmu.2017.01926

Rollings C, Sinclair L, Brady HJM, Cantrell D, Ross S. 2018. Interleukin-2 shapes the cytotoxic T cell proteome and immune environment sensing programs. Science Signaling. 11(526):1-16. Available from: 10.1126/scisignal.aap8112

Ross SH, Cantrell DA. 2018. Signaling and Function of Interleukin-2 in T Lymphocytes. Annual Review of Immunology. 36:411-433. Available from: 10.1146/annurev-immunol-042617-053352

Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, Crocker PR, Tanaka M, Duggimpudi S, Knolle P, Heikenwalder M, Ruland J, Mak TW, Brenner D, Pandyra AA, Hoell JI, Borkhardt A, Häussinger D, Lang KS, Lang PA. 2018. Tumor Necrosis Factor-mediated survival of CD169+ cells promotes immune activation during vesicular stomatitis virus infection. Journal of Virology. 92(3):1-18. Available from: 10.1128/JVI.01637-17

Sinclair L, Neyens D, Ramsay G, Taylor P, Cantrell D. 2018. Single cell analysis of kynurenine and System L amino acid transport in T cells. Nature Communications. 9. Available from: 10.1038/s41467- 018-04366-7.

Sutavani RV, Phair IR, Barker R, McFarlane A, Shpiro N, Lang S, Woodland A, Arthur JSC. 2018. Differential regulation of TLR4 induced IL-10 production in B cells and macrophages reveals a novel role for RSK1 and 2 in B cells. Journal of Biological Chemistry. 293(7):2302-2317. Available from: 10.1074/jbc.M117.805424

van Dinther D, Veninga H, Iborra S, Borg EGF, Hoogterp L, Olesek K, Beijer MR, Schetters STT, Kalay H, Garcia-Vallejo JJ, Franken KL, Cham LB, Lang KS, van Kooyk Y, Sancho D, Crocker PR, den Haan JMM. 2018. Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming. Cell Reports. 22(6):1484-1495. Available from: 10.1016/j.celrep.2018.01.021

Vara Ciruelos D, Dandapani M, Gray A, Agbani EO, Evans AM, Hardie DG. 2018. Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival. Molecular Cancer Research. 16(2):345-357. Available from: 10.1158/1541-7786.MCR-17-0323