University of Dundee

Cell Biology and Immunology Publications 2008

Sinclair, L.V, Finlay, C., Feijoo, C., Cornish, G.H, Gray, A., Ager, A., Okkenhaug, K., Hagenbeek, T.J., Spits, H., and Cantrell, D.A. (2008) Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nature Immunology 9:513-521

Sauer, S., Bruno, L., Hertweck, A., Finlay, D., Leleu, M., Spivakov, M., Knight, Z.A., Cobb, B.S., Cantrell, D., O'Connor, E., Shokat, K.M., Fisher, A.G., and Merkenschlager, M. (2008) T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. Proc.Natl.Acad.Sci.USA. 105(22):7797-802.

Svensson, H.G, West, M.A, Mollahan, P., Prescott, A.R., Zaru, R., and Watts, C. (2008) A role for ARF6 in dendritic cell podosome formation and migration. Eur J Immunol 38: 818-828.

Martin-Granados, C., Philp, A., Oxenham, S.K., Prescott, A.R., and Cohen, P.T.W. (2008) Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. Int J Biochem Cell Biol 40: 2315-32

Stokes, M.J., Guther, M.L.S., Turnock, D.C., Prescott, A.R., Martin, K.L., Alphey, M.S., and Ferguson, MA.J. (2008) The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form Trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation. J Biol Chem 283:16147-61.

James, E.K., Elliott, G.N., Chen, W-M., Bontemps, C., Young, J.P.W., de Faria, S.M., dos Reis Jnr, F.B., Simon, M.F., Gross, E., Loureiro, M.F., Reis, V.M., Perin, L, Boddey, R.M., Hughes, C.E., Moulin, L., Prescott, A.R., and Sprent, J.I. (2008). Infection of legumes by beta-rhizobia. In: Biological Nitrogen Fixation: Towards Poverty Alleviation through Sustainable Agriculture. Eds. F.D. Dakora, S.B.M. Chimphango, A.J. Valentine, C. Elmerich and W.E. Newton. Springer, Dordrecht. 249-250.

Sugiyama, Y., Prescott, A.R., Tholozan, F.M., Ohno, S., and Quinlan, R.A. (2008) Expression and localisation of apical junctional complex proteins in lens epithelial cells. Exp Eye Res. 87: 64-70

Zaru, R., Mollahan, P. & Watts (2008) PDK1 deficiency perturbs Toll-like receptor signalling events and actin cytoskeleton dynamics in dendritic cells. J.Biol.Chem 283: 929-939

Hamilton, G., Colbert, J., Schuettelkopf, A., and Watts, C. (2008) Cystatin F is a cathepsin C directed protease inhibitor regulated by proteolysis. EMBO J. 27: 499-508

Svensson, H., West, M.A., Mollahan, P., Prescott, A.R., Zaru, R., and Watts, C. (2008) A role for ARF6 in dendritic cell podosome formation and migration. Eur.J.Immunol 38: 818-828

Liu, Z., Jang, S.W., Liu, X., Cheng, D., Peng, J., Yepes, M., Li, X.J., Matthews, S., Watts, C., Asano, M., Hara-Nishimura, I., Luo, H.R., and Ye, K. (2008) Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Mol.Cell 29: 665-678

West, M.A., Prescott, A.R., Chan, K.M., Zhou, Z., Rose-John, S., Scheller, J., and Watts, C. (2008) TLR-ligand induced podosome disassembly in dendritic cells is ADAM17 dependent . J Cell Biol 2008 182, 993-1005

Watts, C. (2008) Location, location, location: identifying the neighborhoods of LPS signalling Nat. Immunol. 9: 343-345

Lucocq J. (2008) Quantification of structures and gold labeling in transmission electron microscopy. Methods Cell Biol 88:59-82.

Mayhew, T.M., and Lucocq, J.M. (2008) Developments in cell biology for quantitative immunoelectron microscopy based on thin sections: a review. Histochem Cell Biol 130(2):299-313.

Tsaousis, A.D., Kunji, E.R., Goldberg, A.V., Lucocq, J.M., Hirt, R.P., and Embley T.M. (2008) A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi. Nature 453:553-6.

Bayascas, J.R., Wullschleger, S., Sakamoto, K., García-Martínez, J.M., Clacher, C., Komander, D., van Aalten, D.M., Boini, K.M., Lang, F., Lipina, C., Logie, L., Sutherland, C., Chudek, J.A., van Diepen, J.A., Voshol, P.J., Lucocq, J.M., and Alessi, D.R. (2008) Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol 28:3258-72.

Rousseau, S., Papoutsopoulou, M., Symons, A., Cook, D., Lucocq, J.M., Prescott, A.R., O'Garra, A., Ley, S.C., and Cohen, P. (2008) TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages. J Cell Sci 121:149-54.

Mayhew, T.M., and Lucocq, J.M. (2008) Quantifying immunogold labelling patterns of cellular compartments when they comprise mixtures of membranes (surface-occupying) and organelles (volume-occupying). Histochem Cell Biol 129(3):367-378. Epub

Ducreux, J., Vanbever, R., and Crocker, P.R. (2008) Pegylation of monoclonal antibodies to Sn greatly increase inhibitory potency. Bioconjugate Chemistry in press.

Zucchini, N., Bessou, G., Robbins, S.H., Chasson, L., Raper, A., and Crocker, P.R. (2008) Dalod M: Individual plasmacytoid dendritic cells are major contributors to the production of multiple innate cytokines in an organ-specific manner during viral infection. International immunology 20(1):45-56.

Zimmermann, N., McBride, M.L., Yamada, Y., Hudson, S.A., Jones, C., Cromie, K.D., Crocker, P.R., Rothenberg, M.E., and Bochner, B.S. (2008) Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils. Allergy 63(9):1156-1163.

Zhi, Z.L., Laurent, N., Powell, A.K., Karamanska, R., Fais, M., Voglmeir, J., Wright, A., Blackburn, J.M., Crocker, P.R., and Russell, D.A. (2008) A versatile gold surface approach for fabrication and interrogation of glycoarrays. Chem.bio.chem 9(10):1568-1575.

Sancho-Pelluz, J., Wunderlich, K.A., Rauch, U., Romero, F.J., van Veen, T., Limb, G.A., Crocker, P.R., and Perez, M.T. (2008) Sialoadhesin Expression in Intact Degenerating Retinas and Following Transplantation. Investigative ophthalmology & visual science

McMillan, S.J., and Crocker, P.R. (2008) CD33-related sialic-acid-binding immunoglobulin-like lectins in health and disease. Carbohydrate research 343(12):2050-2056.

Karamanska, R., Clarke, J., Blixt, O., Macrae, J.I., Zhang, J.Q., Crocker, P.R., Laurent, N., Wright, A., Flitsch, S.L., and Russell, D.A. (2008) Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays. Glycoconjugate journal 25(1):69-74.

Cowling, V.H., and Cole, M.D. (2008) An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc Homology Box II. Oncogene 27(9):1327-32.

Cole, M.D., and Cowling, V.H. (2008) Transcription-independent functions of MYC: regulation of translation and DNA replication. Nature Reviews Mol Cel Biol AOP