Division of Molecular Medicine

The Division of Molecular Medicine is located on the 4th Floor of the Medical Sciences Institute. 


Head of Division
: Professor Irwin McLean


Acting Divisional Secretaries: Dr Cathy Whitfield and Mrs Diane Purves

Laboratory Manager: Ms Lynn McKay





 

The Division of Molecular Medicine bridges the two Colleges of Life Sciences and Medicine, Dentistry & Nursing. Its strategic aims are (i) to further strengthen the research ties between the two Colleges; and (ii) to facilitate translation of basic science discoveries into improvements in health and quality of life.  The Division’s main target diseases for experimental medicine development are cancer and skin disease.

The research groups within the Division have substantial funding from Cancer Research UK and The Medical Research Council, as well as a number of charities active in the area of inherited skin disease, particularly The Dystrophic Epidermolysis Bullosa Research Association (DEBRA), Pachyonychia Congenita Project (PC Project), The British Skin Foundation and The National Eczema Society.

The work of the Division is focussed on: functions of the p53 system and its exploitation for development of new anti-cancer drugs; development of therapeutic antibodies for cancer and other diseases; identification of genes involved in human disease; cytoskeleton systems in tissue homeostasis and specialized functions; development of RNA-interference and small molecule drug therapies.

The Division consists of the following collaborating research groups:

Principal Investigator:

Professor Irwin McLean: Skin disease genes and therapy development 

Independent Investigator:

Dr Deena Leslie Pedrioli: siRNA therapy development for skin disorders

Associate Principal Investigator:

Dr Paul Campbell: Ultrasound delivery of therapeutics (Biomedical Physics Group)

Honorary Principal Investigators:
 
Professor Birgit Lane (Emeritus Professor based in Singapore): Cytoskeleton function in epithelial cells (PA: Dr Cathy Whitfield)

Professor Sir David Lane (Emeritus Professor based in Singapore): p53 function and cancer therapy development (PA: Mrs Diane Purves)