Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates, Hauer, M.H., A. Seeber, V. Singh, R. Thierry, R. Sack, A. Amitai, M. Kryzhanovska, J. Eglinger, D. Holcman, T. Owen-Hughes, and S.M. Gasser, Nat Struct Mol Biol, 2017, 10.1038/nsmb.3347,

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes, Sundaramoorthy, R., A.L. Hughes, V. Singh, N. Wiechens, D.P. Ryan, H. El-Mkami, M. Petoukhov, D.I. svergun, B. Treutlein, S. Quack, M. Fischer, J. Michaelis, B. Böttcher, D.G. Norman, and T. Owen-Hughes, eLife, 2017. 6: p. e22510, 10.7554/eLife.22510,

Deciphering Subunit-Specific Functions within SWI/SNF Complexes, Hughes, A.L. and T. Owen-Hughes, Cell Reports, 2017. 18(9): p. 2075-2076,

Unlocking the nucleosome, Flaus, A. and T. Owen-Hughes, Science, 2017. 355(6322): p. 245.

High resolution imaging reveals heterogeneity in chromatin states between cells that is not inherited through cell division. Dickerson D, Gierliński M, Singh V, Kitamura E, Ball G, Tanaka TU, Owen-Hughes T. BMC Cell Biol. 2016 Sep 8;17(1):33. doi: 10.1186/s12860-016-0111-y. PMCID 5016949

The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors, Wiechens, N., Singh, V., Gkikopoulos, T., Schofield, P., Rocha, S., and Owen-Hughes, T. (2016). PLoS genetics 12, e1005940, doi 10.1371/journal.pgen.1005940, PMCID 4809547.

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?, Schurch, N.J., Schofield, P., Gierlinski, M., Cole, C., Sherstnev, A., Singh, V., Wrobel, N., Gharbi, K., Simpson, G.G., Owen-Hughes, T., et al.(2016). RNA 22, 839-851, doi 10.1261/rna.053959.115, PMCID 4878611.

The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3-H4 tetramers and Asf1-H3-H4 complexes, Hammond, C.M., Sundaramoorthy, R., Larance, M., Lamond, A., Stevens, M.A., El-Mkami, H., Norman, D.G., and Owen-Hughes, T. (2016). Nucleic Acids Res 44, 6157-6172, doi 10.1093/nar/gkw209.

Establishment of a promoter-based chromatin architecture on recently replicated DNA can accommodate variable inter-nucleosome spacing, Fennessy, R.T., and Owen-Hughes, T. (2016). Nucleic Acids Res 44, 7189-7203, doi 10.1093/nar/gkw331, PMCID 5009725.

Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment, Gierlinski, M., Cole, C., Schofield, P., Schurch, N.J., Sherstnev, A., Singh, V., Wrobel, N., Gharbi, K., Simpson, G., Owen-Hughes, T., et al.(2015). Bioinformatics doi 10.1093/bioinformatics/btv425.

Modelling multi-protein complexes using PELDOR distance measurements for rigid body minimisation experiments using XPLOR-NIH, Hammond, C.M., Owen-Hughes, T., and Norman, D.G. (2014). Methods 70, 139-153, doi 10.1016/j.ymeth.2014.10.028.

The spatial effect of protein deuteration on nitroxide spin-label relaxation: Implications for EPR distance measurement, El Mkami, H., Ward, R., Bowman, A., Owen-Hughes, T., and Norman, D.G. (2014). J Magn Reson 248, 36-41, doi 10.1016/j.jmr.2014.09.010.

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription, Di Cerbo, V., Mohn, F., Ryan, D.P., Montellier, E., Kacem, S., Tropberger, P., Kallis, E., Holzner, M., Hoerner, L., Feldmann, A., et al.(2014). Elife  DOI 10.7554/eLife.01632.

The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution, Bowman, A., Hammond, C.M., Stirling, A., Ward, R., Shang, W.F., El-Mkami, H., Robinson, D.A., Svergun, D.I., Norman, D.G., and Owen-Hughes, T. (2014). Nucleic Acids Res 42, 6038-6051,  DOI 10.1093/Nar/Gku232.

PICH: a DNA translocase specially adapted for processing anaphase bridge DNA. Biebricher A, Hirano S, Enzlin JH, Wiechens N, Streicher WW, Huttner D, Wang LH, Nigg EA, Owen-Hughes T, Liu Y, Peterman E, Wuite GJ, Hickson ID. Mol Cell. 2013 Sep 12;51(5):691-701. doi: 10.1016/j.molcel.2013.07.016. Epub 2013 Aug 22.  PMID: 23973328

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes. Narlikar GJ, Sundaramoorthy R, Owen-Hughes T. Cell. 2013 Aug 1;154(3):490-503. doi: 10.1016/j.cell.2013.07.011. Review. PMID: 23911317

A comparison of in vitro nucleosome positioning mapped with chicken, frog and a variety of yeast core histones. Allan J, Fraser RM, Owen-Hughes T, Docherty K, Singh V. J Mol Biol. 2013 Nov 15;425(22):4206-22. doi: 10.1016/j.jmb.2013.07.019. Epub 2013 Jul 18. PMID: 23871836

CENP-A confers a reduction in height on octameric nucleosomes. Miell MD, Fuller CJ, Guse A, Barysz HM, Downes A, Owen-Hughes T, Rappsilber J, Straight AF, Allshire RC. Nat Struct Mol Biol. 2013 Jun;20(6):763-5. doi: 10.1038/nsmb.2574. Epub 2013 May 5. PMID: 23644598

Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1. Zhang W, Tyl M, Ward R, Sobott F, Maman J, Murthy AS, Watson AA, Fedorov O, Bowman A, Owen-Hughes T, El Mkami H, Murzina NV, Norman DG, Laue ED. Nat Struct Mol Biol. 2013 Jan;20(1):29-35. doi: 10.1038/nsmb.2446. Epub 2012 Nov 25. PMID: 23178455

Evolutionary insights into genome-wide nucleosome positioning. Singh V, Owen-Hughes T. Genome Biol. 2012;13(9):170. PMID: 23017016

The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4. Watson AA, Mahajan P, Mertens HD, Deery MJ, Zhang W, Pham P, Du X, Bartke T, Zhang W, Edlich C, Berridge G, Chen Y, Burgess-Brown NA, Kouzarides T, Wiechens N, Owen-Hughes T, Svergun DI, Gileadi O, Laue ED. J Mol Biol. 2012 Sep 7;422(1):3-17. doi: 10.1016/j.jmb.2012.04.031. Epub 2012 May 7. PMID: 22575888

Making sense of transcribing chromatin. Owen-Hughes T, Gkikopoulos T. Curr Opin Cell Biol. 2012 Jun;24(3):296-304. doi: 10.1016/ Epub 2012 Mar 10. Review. PMID: 22410403

Micrococcal nuclease does not substantially bias nucleosome mapping. Allan J, Fraser RM, Owen-Hughes T, Keszenman-Pereyra D. J Mol Biol. 2012 Mar 30;417(3):152-64. doi: 10.1016/j.jmb.2012.01.043. Epub 2012 Jan 30. PMID: 22310051

Sulfyhydryl-reactive site-directed cross-linking as a method for probing the tetrameric structure of histones H3 and H4. Bowman A, Owen-Hughes T. Methods Mol Biol. 2012;833:373-87. doi: 10.1007/978-1-61779-477-3_22. PMID: 22183605

A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization. Gkikopoulos T, Schofield P, Singh V, Pinskaya M, Mellor J, Smolle M, Workman JL, Barton GJ, Owen-Hughes T. Science. 2011 Sep 23;333(6050):1758-60. doi: 10.1126/science.1206097. PMID: 21940898

Snf2-family proteins: chromatin remodellers for any occasion. Ryan DP, Owen-Hughes T.  Curr Opin Chem Biol. 2011 Oct;15(5):649-56. doi: 10.1016/j.cbpa.2011.07.022. Epub 2011 Aug 20. Review. PMID: 21862382

Mechanisms for ATP-dependent chromatin remodelling: the means to the end. Flaus A, Owen-Hughes T. FEBS J. 2011 Oct;278(19):3579-95. doi: 10.1111/j.1742-4658.2011.08281.x. Epub 2011 Sep 8. Review. PMID: 21810178

The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains. Ryan DP, Sundaramoorthy R, Martin D, Singh V, Owen-Hughes T. EMBO J. 2011 May 27;30(13):2596-609. doi: 10.1038/emboj.2011.166. PMID: 21623345

The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4. Gkikopoulos T, Singh V, Tsui K, Awad S, Renshaw MJ, Scholfield P, Barton GJ, Nislow C, Tanaka TU, Owen-Hughes T. EMBO J. 2011 May 18;30(10):1919-27. doi: 10.1038/emboj.2011.112. Epub 2011 Apr 19. PMID: 21505420

The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation. Bowman A, Ward R, Wiechens N, Singh V, El-Mkami H, Norman DG, Owen-Hughes T. Mol Cell. 2011 Feb 18;41(4):398-408. doi: 10.1016/j.molcel.2011.01.025. PMID: 21329878

DNA repair factor APLF is a histone chaperone. Mehrotra PV, Ahel D, Ryan DP, Weston R, Wiechens N, Kraehenbuehl R, Owen-Hughes T, Ahel I. Mol Cell. 2011 Jan 7;41(1):46-55. doi: 10.1016/j.molcel.2010.12.008. PMID: 21211722

ATRX: Put me on repeat. Whitehouse I, Owen-Hughes T. Cell. 2010 Oct 29;143(3):335-6. doi: 10.1016/j.cell.2010.10.021. PMID: 21029854

EPR distance measurements in deuterated proteins. Ward R, Bowman A, Sozudogru E, El-Mkami H, Owen-Hughes T, Norman DG. J Magn Reson. 2010 Nov;207(1):164-7. doi: 10.1016/j.jmr.2010.08.002. Epub 2010 Aug 11. PMID: 20805036

The Snf2 homolog Fun30 acts as a homodimeric ATP-dependent chromatin-remodeling enzyme. Awad S, Ryan D, Prochasson P, Owen-Hughes T, Hassan AH. J Biol Chem. 2010 Mar 26;285(13):9477 84. doi: 10.1074/jbc.M109.082149. Epub 2010 Jan 14. PMID: 20075079

Probing the (H3-H4)2 histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling. Bowman A, Ward R, El-Mkami H, Owen-Hughes T, Norman DG. Nucleic Acids Res. 2010 Jan;38(2):695-707. doi: 10.1093/nar/gkp1003. Epub 2009 Nov 13. PMID: 19914933

A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation. Neumann H, Hancock SM, Buning R, Routh A, Chapman L, Somers J, Owen-Hughes T, van Noort J, Rhodes D, Chin JW. Mol Cell. 2009 Oct 9;36(1):153-63. doi: 10.1016/j.molcel.2009.07.027. PMID: 19818718

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Ahel D, Horejsí Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M, West SC, Jackson SP, Owen-Hughes T, Boulton SJ. Science. 2009 Sep 4;325(5945):1240-3. doi: 10.1126/science.1177321. Epub 2009 Aug 6. PMID: 19661379

SWI/SNF and Asf1p cooperate to displace histones during induction of the saccharomyces cerevisiae HO promoter. Gkikopoulos T, Havas KM, Dewar H, Owen-Hughes T. Mol Cell Biol. 2009 Aug;29(15):4057-66. doi: 10.1128/MCB.00400-09. Epub 2009 May 26. PMID: 19470759

Phosphorylation of histone H3 Thr-45 is linked to apoptosis. Hurd PJ, Bannister AJ, Halls K, Dawson MA, Vermeulen M, Olsen JV, Ismail H, Somers J, Mann M, Owen-Hughes T, Gout I, Kouzarides T. J Biol Chem. 2009 Jun 12;284(24):16575-83. doi: 10.1074/jbc.M109.005421. Epub 2009 Apr 10. PMID: 19363025

ATP-dependent looping of DNA by ISWI. Lia G, Indrieri M, Owen-Hughes T, Finzi L, Podesta A, Milani P, Dunlap D. J Biophotonics. 2008 Sep;1(4):280-6. doi: 10.1002/jbio.200810027. PMID: 19343651

Mutations to the histone H3 alpha N region selectively alter the outcome of ATP-dependent nucleosome-remodelling reactions. Somers J, Owen-Hughes T. Nucleic Acids Res. 2009 May;37(8):2504-13. doi: 10.1093/nar/gkp114. Epub 2009 Mar 5. PMID: 19264807

FACT facilitates chromatin transcription by RNA polymerases I and III. Birch JL, Tan BC, Panov KI, Panova TB, Andersen JS, Owen-Hughes TA, Russell J, Lee SC, Zomerdijk JC. EMBO J. 2009 Apr 8;28(7):854-65. doi: 10.1038/emboj.2009.33. Epub 2009 Feb 12. PMID: 19214185

Nucleosomes can invade DNA territories occupied by their neighbors. Engeholm M, de Jager M, Flaus A, Brenk R, van Noort J, Owen-Hughes T. Nat Struct Mol Biol. 2009 Feb;16(2):151-8. doi: 10.1038/nsmb.1551. Epub 2009 Feb 1. PMID: 19182801

Long distance PELDOR measurements on the histone core particle. Ward R, Bowman A, El-Mkami H, Owen-Hughes T, Norman DG. J Am Chem Soc. 2009 Feb 4;131(4):1348-9. doi: 10.1021/ja807918f. PMID: 19138067

MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF. Chang EY, Ferreira H, Somers J, Nusinow DA, Owen-Hughes T, Narlikar GJ. Biochemistry. 2008 Dec 23;47(51):13726-32. doi: 10.1021/bi8016944. PMID: 19035833

ABF1-binding sites promote efficient global genome nucleotide excision repair. Yu S, Smirnova JB, Friedberg EC, Stillman B, Akiyama M, Owen-Hughes T, Waters R, Reed SH. J Biol Chem. 2009 Jan 9;284(2):966-73. doi: 10.1074/jbc.M806830200. Epub 2008 Nov 6. PMID: 18996839

Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms. Ferreira H, Flaus A, Owen-Hughes T. J Mol Biol. 2007 Nov 30;374(3):563-79. Epub 2007 Sep 26. PMID: 17949749

Pyrosequencing positions nucleosomes precisely. Owen-Hughes T, Engeholm M. Genome Biol. 2007;8(6):217. Review. PMID: 17601355

Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability. Ferreira H, Somers J, Webster R, Flaus A, Owen-Hughes T. Mol Cell Biol. 2007 Jun;27(11):4037-48. Epub 2007 Mar 26. PMID: 17387148

Lighting up nucleosome spacing. Ferreira H, Owen-Hughes T. Nat Struct Mol Biol. 2006 Dec;13(12):1047-9. No abstract available.  PMID: 17146458

Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures. Dürr H, Flaus A, Owen-Hughes T, Hopfner KP. Nucleic Acids Res. 2006;34(15):4160-7. Epub 2006 Aug 25. Review. PMID: 16935875

Identification of multiple distinct Snf2 subfamilies with conserved structural motifs. Flaus A, Martin DM, Barton GJ, Owen-Hughes T. Nucleic Acids Res. 2006 May 31;34(10):2887-905. Print 2006. PMID: 16738128

Nucleosome dynamics. Stockdale C, Bruno M, Ferreira H, Garcia-Wilson E, Wiechens N, Engeholm M, Flaus A, Owen-Hughes T. Biochem Soc Symp. 2006;(73):109-19. Review. PMID: 16626292

Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes. Stockdale C, Flaus A, Ferreira H, Owen-Hughes T. J Biol Chem. 2006 Jun 16;281(24):16279-88. Epub 2006 Apr 10. PMID: 16606615

The role of Snf2-related proteins in cancer. Owen-Hughes T.Ernst Schering Res Found Workshop. 2006;(57):47-59. Review.PMID:16568948

Direct observation of DNA distortion by the RSC complex. Lia G, Praly E, Ferreira H, Stockdale C, Tse-Dinh YC, Dunlap D, Croquette V, Bensimon D, Owen-Hughes T.Mol Cell. 2006 Feb 3;21(3):417-25.PMID:16455496

De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases. Gowher H, Stockdale CJ, Goyal R, Ferreira H, Owen-Hughes T, Jeltsch A. Biochemistry. 2005 Jul 26;44(29):9899-904.PMID:16026162

The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression. Roche KC, Wiechens N, Owen-Hughes T, Perkins ND.Oncogene. 2004 Oct 28;23(50):8185-95.PMID:15378006

Mechanisms for ATP-dependent chromatin remodelling: farewell to the tuna-can octamer? Flaus A, Owen-Hughes T.Curr Opin Genet Dev. 2004 Apr;14(2):165-73. Review.PMID:15196463

The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repair. Yu S, Owen-Hughes T, Friedberg EC, Waters R, Reed SH. DNA Repair (Amst). 2004 Mar 4;3(3):277-87.PMID:15177043

Site-specific attachment of reporter compounds to recombinant histones. Bruno M, Flaus A, Owen-Hughes T.Methods Enzymol. 2004;375:211-28. PMID:14870669

Sin mutations alter inherent nucleosome mobility. Flaus A, Rencurel C, Ferreira H, Wiechens N, Owen-Hughes T.EMBO J. 2004 Jan 28;23(2):343-53. Epub 2004 Jan 15.PMID:14726954

Molecular biology. Breaking the silence. Owen-Hughes T, Bruno M. Science. 2004 Jan 16;303(5656):324-5. No abstract available.  PMID:14726582

Histone H2A/H2B dimer exchange by ATP-dependent chromatin remodeling activities. Bruno M, Flaus A, Stockdale C, Rencurel C, Ferreira H, Owen-Hughes T.Mol Cell. 2003 Dec;12(6):1599-606.PMID:14690611

Dynamic properties of nucleosomes during thermal and ATP-driven mobilization. Flaus A, Owen-Hughes T. Mol Cell Biol. 2003 Nov;23(21):7767-79.PMID:14560021

Colworth memorial lecture. Pathways for remodelling chromatin.

Owen-Hughes T. Biochem Soc Trans. 2003 Oct;31(Pt 5):893-905. Review.PMID:14505445

Mechanisms for nucleosome mobilization.Flaus A, Owen-Hughes T.Biopolymers. 2003 Apr;68(4):563-78.PMID:12666181

Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme. Whitehouse I, Stockdale C, Flaus A, Szczelkun MD, Owen-Hughes T.Mol Cell Biol. 2003 Mar;23(6):1935-45.PMID:12612068

Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription. Rouleau N, Domans'kyi A, Reeben M, Moilanen AM, Havas K, Kang Z, Owen-Hughes T, Palvimo JJ, Jänne OA. Mol Biol Cell. 2002 Jun;13(6):2106-19.PMID:12058073

ATP-dependent chromatin remodeling activities. Havas K, Whitehouse I, Owen-Hughes T.Cell Mol Life Sci. 2001 May;58(5-6):673-82. Review.PMID:11437229

Mechanisms for ATP-dependent chromatin remodelling. Flaus A, Owen-Hughes T.Curr Opin Genet Dev. 2001 Apr;11(2):148-54. Review.PMID:11250137

Generation of superhelical torsion by ATP-dependent chromatin remodeling activities. Havas K, Flaus A, Phelan M, Kingston R, Wade PA, Lilley DM, Owen-Hughes T.Cell. 2000 Dec 22;103(7):1133-42.PMID:11163188

Mechanisms for ATP-dependent chromatin remodelling.Whitehouse I, Flaus A, Havas K, Owen-Hughes T.Biochem Soc Trans. 2000;28(4):376-9. Review.PMID:10961923

Analysis of nucleosome disruption by ATP-driven chromatin remodeling complexes. Owen-Hughes T, Utley RT, Steger DJ, West JM, John S, Côté J, Havas KM, Workman JL.Methods Mol Biol. 1999;119:319-31. Review. No abstract available. PMID:10804522

Nucleosome mobilization catalysed by the yeast SWI/SNF complex. Whitehouse I, Flaus A, Cairns BR, White MF, Workman JL, Owen-Hughes T.Nature. 1999 Aug 19;400(6746):784-7.PMID:10466730

Regulation of transcription by multisubunit complexes that alter nucleosome structure. Steger DJ, Utley RT, Grant PA, John S, Eberharter A, Côté J, Owen-Hughes T, Ikeda K, Workman JL.Cold Spring Harb Symp Quant Biol. 1998;63:483-91. Review. No abstract available. PMID:10384312

Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Barlev NA, Poltoratsky V, Owen-Hughes T, Ying C, Liu L, Workman JL, Berger SL.Mol Cell Biol. 1998 Mar;18(3):1349-58.PMID:9488450

Analysis of transcription factor-mediated remodeling of nucleosomal arrays in a purified system. Steger DJ, Owen-Hughes T, John S, Workman JL.Methods. 1997 Jul;12(3):276-85.PMID:9237171

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Grant PA, Duggan L, Côté J, Roberts SM, Brownell JE, Candau R, Ohba R, Owen-Hughes T, Allis CD, Winston F, Berger SL, Workman JL.Genes Dev. 1997 Jul 1;11(13):1640-50.PMID:9224714

SWI/SNF stimulates the formation of disparate activator-nucleosome complexes but is partially redundant with cooperative binding. Utley RT, Côté J, Owen-Hughes T, Workman JL.J Biol Chem. 1997 May 9;272(19):12642-9.

Select item 898023267.

The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Mizzen CA, Yang XJ, Kokubo T, Brownell JE, Bannister AJ, Owen-Hughes T, Workman J, Wang L, Berger SL, Kouzarides T, Nakatani Y, Allis CD. Cell. 1996 Dec 27;87(7):1261-70.PMID:8980232

Remodeling the chromatin structure of a nucleosome array by transcription factor-targeted trans-displacement of histones. Owen-Hughes T, Workman JL.EMBO J. 1996 Sep 2;15(17):4702-12.PMID:8887561

Persistent site-specific remodeling of a nucleosome array by transient action of the SWI/SNF complex. Owen-Hughes T, Utley RT, Côté J, Peterson CL, Workman JL.Science. 1996 Jul 26;273(5274):513-6.PMID:8662543

In vitro analysis of transcription factor binding to nucleosomes and nucleosome disruption/displacement. Utley RT, Owen-Hughes TA, Juan LJ, Côté J, Adams CC, Workman JL.Methods Enzymol. 1996;274:276-91. No abstract available. PMID:8902812

DNA twist, flexibility and transcription of the osmoregulated proU promoter of Salmonella typhimurium. Jordi BJ, Owen-Hughes TA, Hulton CS, Higgins CF.EMBO J. 1995 Nov 15;14(22):5690-700.PMID:8521826

Stimulation of transcription factor binding and histone displacement by nucleosome assembly protein 1 and nucleoplasmin requires disruption of the histone octamer. Walter PP, Owen-Hughes TA, Côté J, Workman JL. Mol Cell Biol. 1995 Nov;15(11):6178-87.PMID:7565770

The chromatin-associated protein H-NS alters DNA topology in vitro. Tupper AE, Owen-Hughes TA, Ussery DW, Santos DS, Ferguson DJ, Sidebotham JM, Hinton JC, Higgins CF.EMBO J. 1994 Jan 1;13(1):258-68.PMID:8306968

Experimental analysis of chromatin function in transcription control. Owen-Hughes T, Workman JL.Crit Rev Eukaryot Gene Expr. 1994;4(4):403-41. Review.PMID:7734837

The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression. Owen-Hughes TA, Pavitt GD, Santos DS, Sidebotham JM, Hulton CS, Hinton JC, Higgins CF.Cell. 1992 Oct 16;71(2):255-65.PMID:1423593

Protein H1: a role for chromatin structure in the regulation of bacterial gene expression and virulence? Higgins CF, Hinton JC, Hulton CS, Owen-Hughes T, Pavitt GD, Seirafi A.Mol Microbiol. 1990 Dec;4(12):2007-12. Review.PMID:2128526

Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria. Hulton CS, Seirafi A, Hinton JC, Sidebotham JM, Waddell L, Pavitt GD, Owen-Hughes T, Spassky A, Buc H, Higgins CF.Cell. 1990 Nov 2;63(3):631-42.PMID:2171779

The effect of DnaA protein levels and the rate of initiation at oriC on transcription originating in the ftsQ and ftsA genes: in vivo experiments.  Masters M, Paterson T, Popplewell AG, Owen-Hughes T, Pringle JH, Begg KJ.Mol Gen Genet. 1989 Apr;216(2-3):475-83.PMID:2546042