Publications 2009

Hsu C-K, Akiyama M, Nemoto-Hasebe I, Nomura T, Sandilands A, Chao S-C, Lee Y-Y, Sheu H-M, McLean WHI and Shimizu H (2009) Analysis of Taiwanese ichthyosis vulgaris families further demonstrates differences in FLG mutations between European and Asian populations. Br J Dermatol, 161: 448-51 [Epub ahead of print March 26th 2009].  (Pub Med ID: 19416262)

Brown SJ and McLean WHI (2009) Eczema genetics: current state of knowledge and future goals. J Invest Dermatol 129:543-52. (Pub Med ID: 19209157)

Van Limbergen J, Russell JK, Nimmo ER, Zhao Y, Liao H, Drummond HE, Davies G, Gillett PM, McGrogan P, Weaver LT, Bisset WM, Mahdi G, Wilson DC, Brown SJMcLean WHI and Satsangi J (2009)  Filaggrin loss-of-function variants are associated with atopic co-morbidity in paediatric inflammatory bowel disease.  Inflammatory  Bowel Diseases, 15: 1492-8 [Epub ahead of print 30th April 2009].  (Pub Med ID: 19408338)

Sandilands A, Sutherland C, Irvine AD and McLean WHI (2009)  Filaggrin in the frontline: role in skin barrier function and disease.  J Cell Sci 122: 1285-1294.  (Pub Med ID: 19386895)

Rodriguez S, Hall, AJ, Granell R, McLean WHI, Irvine AD, Palmer CNA Davey-Smith G, Henderson J and Day INM (2009) Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5377 children from the ALSPAC Cohort. PLoS ONE 4(6): e5784. doi:10.1371/journal.pone.0005784.  (Pub Med ID: 19492053)

Sun M, Li N, Dong W, Chen Z, Liu Q, Xu Y, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WHI, Dong Q, Wang MR, Yu J, He L, Lo WH, Zhang X (2009) Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia. Am J Hum Genet 84: 807-813 [Epub ahead of print 21st May 2009].  (Pub Med ID: 19463983)

Brown SJ, Relton CL, Liao H, Zhao Y, Sandilands AMcLean WHI, Cordell HJ and Reynolds NJ (2009) Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 schoolchildren. Br J Dermatol, 161: 884-9. [Epub ahead of print, 11th Jun 2009].  (Pub Med ID: 19681860)

Zamiri M, Smith FJD, Campbell LE, Tetley L, Eady RA, Hodgins MB, McLean WHI, Munro CS (2009) Mutation in DSG1 causing autosomal dominant striate palmoplantar keratoderma. Br J Dermatol, 161: 692-4. [Epub ahead of print, 25th June 2009].  (Pub Med ID: 19558595)

Wilson NJ, Messenger AG, Leachman SA, O’Toole EA, Lane EB, McLean WHI and Smith FJD (2010) Keratin K6c mutations cause focal palmoplantar keratoderma. J Invest Dermatol,130:425-9 [Epub ahead of print, 16th Jul 2009].  (Pub Med ID: 19609311)

Gass JK, Wilson NJ, Smith FJD, Lane EB, McLean WHI, Rytina E, Salvary I and Burrows NP (2009) Steatocystoma multiplex, oligodontia and partial persistent primary dentition associated with a novel keratin 17 mutation.  Br J Dermatol, 161: 1396-8. [Epub ahead of print, 31st Jul 2009].  (Pub Med ID: 19659471)Nemoto-

Hasebe I, Akiyama M, Nomura T, Sandilands AMcLean WHI and Shimizu H (2009) FLG mutation p.Lys4021X in the C-terminal imperfect filaggrin repeat in Japanese atopic eczema patients. Br J Dermatol, 161: 1387-90 [Epub ahead of print, 7th Aug 2009].  (Pub Med ID: 19663875)

O’Regan GM, Sandilands AMcLean WHI and Irvine AD (2009) Filaggrin in atopic dermatitis. J Allergy Clin Immun,124(3S2):R2-R6.  (Pub Med ID: 19720209)

Hamill KJ, Langbein L, Jones JCR and McLean WHI (2009) Identification of a novel family of laminin N-terminal alternate splice isoforms: structural and functional characterization.  J BiolChem, 284: 35588-96. [Epub ahead of print 22nd Sept 2009].  (Pub Med ID: 19773554)

Schuttelaar ML, Kerkhof M, Jonkman MF, Koppelman GH, Brunekreef B, de Jongste JC, Wijga A, McLean WHI and Postma DS (2009) Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure. Allergy 64:1758-1765 [Epub ahead of print 14th Oct 2009].  (Pub Med ID: 19839980)