University of Dundee

‘The Role of CSF1R in macrophage development and disease'

Event Date: 
Wednesday, November 13, 2019 - 13:00
Event Location: 
CTIR Sir Kenneth and Lady Noreen Murray Seminar Room . CTIR 284 - Discovery Centre
Host: 
Professor Simon Arthur
Event Speaker: 
Dr Clare Pridans
Institution: 
University of Edinburgh
Event Type: 
Seminar
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CSI/TIG Seminar

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The role of Csf1r in macrophage development and disease

Signalling via the Colony stimulating factor 1 receptor (Csf1r) is important for the survival, differentiation and proliferation of macrophages. Macrophages play important roles during development, the immune response and are implicated in numerous diseases. Clare will discuss the impact of reduced and enhanced Csf1r signalling, the role of CSF1R mutations in human neurodegeneration and highlight the important differences between mouse and rat models.