University of Dundee

“Harnessing biological insight to accelerate tuberculosis drug discovery”

Event Date: 
Tuesday, February 27, 2018 - 09:00 to 10:00
Event Location: 
WTB Seminar Rooms
Host: 
Professor Paul Wyatt FRSE
Event Speaker: 
Professor Valerie Mizrahi
Institution: 
Institute of Infectious Disease and Molecular Medicine, University of Cape Town
Event Type: 
Seminar
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All Welcome!

 

In this talk, I will highlight the way in which advances in our understanding of the biology of Mycobacterium tuberculosis have been applied in TB drug discovery by enabling the discovery of high-quality lead compounds coupled with the identification and validation of new TB drug targets. I will illustrate the approach employed in contemporary TB drug discovery consortia using a case study from my own laboratory, and will close with some thoughts on the scientific challenges in achieving the aspirational goal of dramatic treatment-shortening for TB.