University of Dundee

Biologist (up to 2 positions)

Unit: 
Biological Chemistry and Drug Discovery
Job Reference: 
LS0103
Closing Date: 
Friday, October 21, 2011
Salary: 
Grade 7 (£29,099 - £35,788)

The Drug Discovery Unit (DDU) (see http://www.drugdiscovery.dundee.ac.uk) is a fully integrated drug discovery operation based within a world class Life Sciences research environment. Its remit is to complement BioPharma activities by tackling both neglected diseases (trypanosomiasis, leishmaniasis and malaria) and early stage small molecule validation of novel targets & mechanisms across a range of potential therapeutics areas. The DDU works to Biotech style philosophy and standards incorporating, dynamic, goal driven project management based on Target Product Profiles and Compound Selection Criteria. The project goals are therapeutic area dependent but range from quality leads demonstrating disease model proof of concept, through to pre-clinical candidates.

We are currently looking for a highly motivated biologist to be part of a BioPharma experienced, multi-disciplinary team in the DDU. The post is available from 1st October 2011 for 12 months and salary will depend on experience. This is a unique opportunity to gain experience in industry-style drug discovery within an academic setting.

Your responsibilities:
• Developing, assessing and proposing credible molecular targets
• Providing high content imaging expertise to allow screening of intracellular parasites
• Playing leadership roles in program teams or cross-discipline workgroups
• Providing innovative ideas in the development of the unit’s capabilities
• Culturing parasites and human host cell lines
• Developing relevant cell based and biochemical assays
• Screening and profiling novel compounds
• Designing and performing detailed mechanism of action studies
• Carrying out data analysis and relevant quality assurance protocols
• Working collaboratively with members of the Drug Discovery Unit and academic or industrial collaborators to support drug discovery programs

Your qualifications:
• A first or second degree in biochemistry, pharmacology or other relevant biological discipline
• Experience of culturing parasites in Category 3 facilities is essential
• A high level of high content imaging expertise is essential
• A track record of culturing a variety of cell types
• Competency in a range of assay techniques
• Strong interpersonal, communication and presentation skills
• A demonstrated ability to work in an organised manner and to standard operating procedures is essential
• Experience of working in drug discovery is highly desired but is not essential
• An ability to be proactive, productive and to work effectively in teams is required.

Dundee, set on the east-coast of Scotland, lies in an area of outstanding natural beauty, including large sandy beaches and challenging hills. Rainfall charts show this is one of the sunniest and driest places in the UK.

For informal discussion about the post please contact Dr David Gray, tel: (01382) 386247 or e-mail: d.w.gray@dundee.ac.uk.

How to Apply:
To apply on-line please visit: www.dundee.ac.uk/jobs. If you are unable to apply on-line please contact Human Resources on (01382) 386209 (answering machine) for an application pack. Please quote reference number LS0103. Closing Date: 21 October 2011.

The University of Dundee is committed to equal opportunities and welcomes applications from all sections of the community.

The University of Dundee is a Scottish Registered Charity, No. SC015096.