Abstract: Structural organisation of eukaryotic cell is fundamental in health and disease. The cells' volume can be divided into two distinct regions: cytoplasm and nucleoplasm. Although the molecular tools that organise these two regions differ, the general principles are conserved.
School of Research
The productivity of cereal crops could get a boost in the future thanks to the discovery of new roles for a master gene regulator that influences the development of barley florets, furthering the understanding of grain development including impacts on grain shape and yield.
A new study from the University of Dundee and the James Hutton Institute, working with partners in the UK and Australia, has shown that a gene encoding a protein called HvAPETALA2 (HvAP2) has a role in the development of florets and grain.
Amphista Therapeutics, a University of Dundee spinout company, has announced a near-£40 million investment that will further its work to develop new drugs for a range of diseases.
Amphista is a biopharmaceutical company creating first-in-class therapeutics that harness the body’s natural processes to selectively and efficiently degrade and remove disease-causing proteins. The company is a spinout from Professor Alessio Ciulli’s labs at the University’s School of Life Sciences.
Researchers at the University of Dundee have identified novel interaction sites on the mRNA Capping Enzyme that are essential for its activity. The results, which have implications for how gene expression is regulated in human cells and could lead to new treatment strategies for diseases such as cancer, are published in the journal Nucleic Acids Research.
A University of Dundee masterclass could help to inspire the city’s next generation of bio-entrepreneurs. Dr Deborah O’Neil, founder and CEO of leading clinical-stage biotechnology company Novabiotics, will be sharing her experiences in the world of business as host of the University’s latest Entrepreneurial Masterclass.
With more than two decades of experience in anti-infective drug discovery research and development, she will share the secrets of her success at "Actually Doing It - The Start of Your Journey as a Bio-Entrepreneur,” on Wednesday 17 March.
The impact that an ageing population has on the health and wellbeing of individuals, groups, communities and societies, and what we can do to address these challenges, will be the focus of a University of Dundee lecture.