University of Dundee

Medical Research Council Protein Phosphorylation and Ubiquitylation Unit

Short Code: 
MRCPPU

Postdoctoral Research Assistant

Summary of Job Purpose and Principal Duties:

Therapeutically activating autophagy in vivo

We are seeking a talented postdoctoral fellow to be involved in the development of pharmacological activators of autophagy and to identify new biology in this area. Work will be carried out in the laboratory of Ian Ganley at the Medical Research Council’s Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) in Dundee. This is part of a unique academic-industrial collaboration led by Samsara Therapeutics.

Postdoctoral Research Assistant

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 40 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

Postdoctoral Researcher

Summary of Job Purpose and Principal Duties:

Post-doctoral position: Characterisation of physiological substrates of the NEK1 kinase complex and the functional impact of disease-causing mutations

The Rouse lab is interested in how cells sense, signal and repair damaged DNA, and how they cope with DNA damage. The goal of the lab is to work out the molecular mechanisms underlying DNA damage signalling and repair, and how these processes are controlled by phosphorylation and ubiquitylation.

Repair of mitochondrial recycling defect linked to Parkinson’s disease

Treating mice that have a Parkinson’s disease-causing mutation with a small molecule compound restores the removal of damaged mitochondria from their brain cells, shows a study published today in eLife.

The findings may help explain what goes wrong in dopamine-producing brain cells in people with mutations that cause Parkinson’s disease.

Parkinson’s disease is caused by the progressive loss of brain cells that produce dopamine. This causes the hallmark symptoms of the disease, including tremors, rigid movements, sleep problems and dementia.

Postdoctoral Research Assistant

Physiological implications of AMPK activation on autophagy and mitophagy

We are seeking a talented postdoctoral fellow to work in the laboratory of Ian Ganley at the Medical Research Council’s Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) in Dundee. This is part of a highly collaborative project led by Kei Sakamoto’s group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR, University of Copenhagen).

Thirty days of graft raises £40,000 for Parkinson’s research

Dozens of dedicated fundraisers have smashed a fundraising target to support Parkinson’s research at the University of Dundee.

The University’s 30 Days Challenge has raised over £40,000 after fundraisers cycled, ran, hula-hooped and baked their way through June for the cause.

The final tally demolished the initial £10,000 target set by organisers, with the event having captured the imagination of donors across the country, as well as television personality and former University Rector Lorraine Kelly.

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