University of Dundee

Biological Chemistry and Drug Discovery

Short Code: 
BCDD

Trypanosomes break more rules: evidence for the convergent evolution of glycosyltransferase function

Glycosyltransferases (GTs) are enzymes that transfer sugars from donor to an acceptor molecule. There are dozens of GT gene families, classified by sequence, sequence motifs and enzymatic function.

GTs are defined by their donor and acceptor specificities and the type of glycosidic linkage they make. For example, a UDP-Gal : ßGal ß1-3 galactosyltransferase transfers galactose from UDP-Gal to a ßGal acceptor residue in a ß1-3 linkage (making a Galß1-3Galß1-R product). 

Grade 2 Technical Assistant - Laboratory Cleaner

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high-quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 40 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

Synthetic Medicinal Chemist

The Drug Discovery Unit (DDU) (http://www.drugdiscovery.dundee.ac.uk) is a fully integrated drug discovery operation based within a world class Life Sciences research environment.

The DDU is a globally acknowledged centre of excellence for drug discovery. The DDU collaborates with partners to translate world-class biology research into novel drug targets and candidate drugs to address unmet medical need across our two areas of activity, Diseases of the Developing World and Innovative Targets Portfolio.

Junior Bioanalyst

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

WCAIR Medicinal Chemistry Trainer

The Wellcome Centre for Anti-Infectives Research (WCAIR) Training programme is seeking a personable and enthusiastic individual to take up the post of a Medicinal Chemistry Trainer. WCAIR builds on world-leading work at the University of Dundee, including within the Drug Discovery Unit (DDU), to find new drugs to treat diseases of the developing world such as malaria, tuberculosis, leishmaniasis and Chagas disease (see www.wcair.dundee.ac.uk).

Computational Drug Design and Molecular Modelling Scientist (PROTAC drug discovery)

We are seeking a highly motivated computational chemist to join a multi-disciplinary drug discovery team based in a new Centre for Targeted Protein Degradation (CeTPD) within Dundee’s School of Life Sciences (https://www.lifesci.dundee.ac.uk/news/2021/apr/14/first-its-kind-centre-lead-protein-degradation-revolution).

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