University of Dundee

Biological Chemistry and Drug Discovery

Short Code: 
BCDD

Three heads are better than two in drug discovery concept

Researchers from the University of Dundee and Promega Corporation have shown how a “three-headed hydra” significantly improves efficacy in a field of chemical biology that is revolutionising drug discovery.

Targeted protein degradation co-opts the cell’s natural disposal systems to remove disease-causing proteins and is applicable to diverse therapeutic areas including oncology, inflammation, dermatology, immunology and respiratory diseases.

Tag tech provides insight into undruggable diseases

Scientists at the University of Dundee have developed a new technology that provides a greater understanding into the biology of ‘undruggable’ diseases.

Cells are composed of thousands of interacting proteins and their malfunction is a primary mechanism of disease development. Drug discovery scientists’ goal is to identify these aberrant proteins, understand their function and develop novel compounds to target them.

Senior Biology Technician

Within the University of Dundee, the newly announced Centre for Targeted Protein Degradation (CeTPD) due to open in early 2022 is being created as a first of its kind Centre leading a number of internationally significant projects in the burgeoning new area of translational chemical biology and targeted protein degradation. The goal of CeTPD is to innovate a next-generation of small-molecule platforms and modalities to advance chemical and biological insights and therapeutic targets related to human diseases.

Senior Chemistry Technician

Within the University of Dundee, the newly announced Centre for Targeted Protein Degradation (CeTPD) due to open in early 2022 is being created as a first of its kind Centre leading a number of internationally significant projects in the burgeoning new area of translational chemical biology and targeted protein degradation. The goal of CeTPD is to innovate a next-generation of small-molecule platforms and modalities to advance chemical and biological insights and therapeutic targets related to human diseases.

Senior Drug Discovery Scientist (Cell Biology)

Within the University of Dundee, the newly announced Centre for Targeted Protein Degradation (CeTPD) is being created as a first of its kind Centre leading a number of internationally significant projects in the burgeoning new area of translational chemical biology and targeted protein degradation. The goal of CeTPD is to innovate the next-generation of small-molecule platforms and modalities to advance chemical and biological insights and therapeutic targets related to human diseases.

Senior Drug Discovery Scientist (Medicinal Chemistry)

Within the University of Dundee, the newly announced Centre for Targeted Protein Degradation (CeTPD) is being created as a first of its kind Centre leading a number of internationally significant projects in the burgeoning new area of translational chemical biology and targeted protein degradation. The goal of CeTPD is to innovate the next-generation of small-molecule platforms and modalities to advance chemical and biological insights and therapeutic targets related to human diseases.

Senior Drug Discovery Scientist (Structural Biology / Biophysics)

Within the University of Dundee, the newly announced Centre for Targeted Protein Degradation (CeTPD) is being created as a first of its kind Centre leading a number of internationally significant projects in the burgeoning new area of translational chemical biology and targeted protein degradation. The goal of CeTPD is to innovate the next-generation of small-molecule platforms and modalities to advance chemical and biological insights and therapeutic targets related to human diseases.

Senior Postdoctoral Scientist (Structural Biology & Biophysics)

Within the University of Dundee, the newly announced Centre for Targeted Protein Degradation (CeTPD) due to open in early 2022 is being created as a first of its kind Centre leading a number of internationally significant projects in the burgeoning new area of translational chemical biology and targeted protein degradation. The goal of CeTPD is to innovate a next-generation of small-molecule technology platforms and modalities to advance chemical and biological insights and therapeutic targets related to human diseases.

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