The Wellcome Centre for Anti-Infectives Research (WCAIR) aims to tackle the urgent unmet medical need and lack of drug discovery research for Neglected Tropical Diseases (NTDs). WCAIR consolidates the existing world-leading NTD drug discovery expertise within the Drug Discovery Unit, the Mode of Action group and the Parasitology research groups providing a continuum from discovery science to pre-clinical candidate selection.
With an initial focus on visceral leishmaniasis (VL) and Chagas’ disease (CD) the Centre will deliver high-quality pre-clinical drug candidate for each disease. To achieve our research will include:
· Innovate drug discovery approaches for VL and CD, including developing in silico and animal models that have improved prediction of Pharmacokinetic/Pharmacodynamic relationships and clinical efficacy.
· Increased exploitation of novel drug targets, through structure-based drug discovery.
· Develop tool compounds with known pharmacology to enable further understanding of parasite biology.
· Improve the efficiency of drug discovery by establishing groups to facilitate compound scale up, compound purification and formatting.
For further information about WCAIR please click here.
The application portal has now closed the 2019 applications.