University of Dundee

Biological Chemistry and Drug Discovery 2011

Abdelwahab, N. Z., Urbaniak, M. D., Ferguson, M. A. and Crossman, A. T. (2011) Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei. Carbohydrate research. 346, 708-714
doi; 10.1016/j.carres.2011.02.004
PMID;3125106  PMC21377660

Anderson, J. S., Dhatt, H. S., Ferguson, M. A., Lopez-Larson, M., Schrock, L. E., House, P. A. and Yurgelun-Todd, D. (2011) Functional connectivity targeting for deep brain stimulation in essential tremor. AJNR Am J Neuroradiol. 32, 1963-1968
doi; 10.3174/ajnr.A2638
PMID;3217124  PMC21885716

Anderson, J. S., Ferguson, M. A., Lopez-Larson, M. and Yurgelun-Todd, D. (2011) Connectivity gradients between the default mode and attention control networks. Brain Connect. 1, 147-157
doi; 10.1089/brain.2011.0007
PMID;3209669  PMC22076305

Anderson, J. S., Ferguson, M. A., Lopez-Larson, M. and Yurgelun-Todd, D. (2011) Reproducibility of single-subject functional connectivity measurements. AJNR Am J Neuroradiol. 32, 548-555
doi; 10.3174/ajnr.A2330
PMID;3205089  PMC21273356

Baragana, B., McCarthy, O., Sanchez, P., Bosch-Navarrete, C., Kaiser, M., Brun, R., Whittingham, J. L., Roberts, S. M., Zhou, X. X., Wilson, K. S., Johansson, N. G., Gonzalez-Pacanowska, D. and Gilbert, I. H. (2011) beta-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. Bioorg Med Chem. 19, 2378-2391
doi; 10.1016/j.bmc.2011.02.012

Barrack, K. L., Tulloch, L. B., Burke, L. A., Fyfe, P. K. and Hunter, W. N. (2011) Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site. Acta Crystallogr Sect F Struct Biol Cryst Commun. 67, 33-37
doi; 10.1107/S174430911004724X
PMID;3079966  PMC21206018

Baschong, W., Wittlin, S., Inglis, K. A., Fairlamb, A. H., Croft, S. L., Kumar, T. R., Fidock, D. A. and Brun, R. (2011) Triclosan is minimally effective in rodent malaria models. Nat Med. 17, 33-34; author reply 34-35
doi; nm0111-33 [pii]

Bickerton, G. R., Higueruelo, A. P. and Blundell, T. L. (2011) Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database. BMC Bioinformatics. 12, 313
doi; 10.1186/1471-2105-12-313
PMID;3161047  PMC21801404

Capes, A. S., Crossman, A. T., Webster, L. A., Ferguson, M. A. and Gilbert, I. H. (2011) Tetrahedron Lett. 52, 7091-7094
doi; 10.1016/j.tetlet.2011.10.090
PMID;3314918  PMC22505782

Cappel, D., Wahlstrom, R., Brenk, R. and Sotriffer, C. A. (2011) Probing the dynamic nature of water molecules and their influences on ligand binding in a model binding site. J Chem Inf Model. 51, 2581-2594
doi; 10.1021/ci200052j

Cleghorn, L. A., Woodland, A., Collie, I. T., Torrie, L. S., Norcross, N., Luksch, T., Mpamhanga, C., Walker, R. G., Mottram, J. C., Brenk, R., Frearson, J. A., Gilbert, I. H. and Wyatt, P. G. (2011) Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3. ChemMedChem. 6, 2214-2224
doi; 10.1002/cmdc.201100344
PMID;3272345  PMC21913331

Daldrop, P., Reyes, F. E., Robinson, D. A., Hammond, C. M., Lilley, D. M., Batey, R. T. and Brenk, R. (2011) Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem Biol. 18, 324-335
doi; 10.1016/j.chembiol.2010.12.020
PMID;3119931  PMC21439477

Dawson, A., Fyfe, P. K., Gillet, F. and Hunter, W. N. (2011) Exploiting the high-resolution crystal structure of Staphylococcus aureus MenH to gain insight into enzyme activity. Bmc Structural Biology. 11doi; 19

Dixon, M. J., Gray, A., Boisvert, F. M., Agacan, M., Morrice, N. A., Gourlay, R., Leslie, N. R., Downes, C. P. and Batty, I. H. (2011) A screen for novel phosphoinositide 3-kinase effector proteins. Molecular & cellular proteomics : MCP. 10, M110 003178
doi; 10.1074/mcp.M110.003178
PMID;3069342  PMC21263009

Dorfmueller, H. C., Borodkin, V. S., Blair, D. E., Pathak, S., Navratilova, I. and van Aalten, D. M. (2011) Substrate and product analogues as human O-GlcNAc transferase inhibitors. Amino Acids. 40, 781-792
doi; 10.1007/s00726-010-0688-y
PMID;3040809  PMC20640461

Dow, G. S., Milner, E., Bathurst, I., Bhonsle, J., Caridha, D., Gardner, S., Gerena, L., Kozar, M., Lanteri, C., Mannila, A., McCalmont, W., Moon, J., Read, K. D., Norval, S., Roncal, N., Shackleford, D. M., Sousa, J., Steuten, J., White, K. L., Zeng, Q. and Charman, S. A. (2011) Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice. Malar J. 10, 150
doi; 10.1186/1475-2875-10-150
PMID;3128011  PMC21645370

Fairlamb, A. and Cole, S. (2011) Antimicrobial drug discovery. Future Microbiology. 6, 601-602
doi; 10.2217/fmb.11.54

Field, M. C., Sali, A. and Rout, M. P. (2011) Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coat. J Cell Biol. 193, 963-972
doi; 10.1083/jcb.201102042
PMID;3115789  PMC21670211

Frank, R. A., Rucker, D. W., Ferguson, M. A. and Sweeney, T. J. (2011) Evidence requirements for innovative imaging devices: from concept to adoption. J Am Coll Radiol. 8, 124-131
doi; 10.1016/j.jacr.2010.06.025

Gabernet-Castello, C., Dubois, K. N., Nimmo, C. and Field, M. C. (2011) Rab11 function in Trypanosoma brucei: identification of conserved and novel interaction partners. Eukaryot Cell. 10, 1082-1094
doi; 10.1128/EC.05098-11
PMID;3165442  PMC21642507

Gay, L. M., Zheng, X. and van Aalten, D. M. (2011) Molecular recognition: O-GlcNAc transfer: size matters. Nat Chem Biol. 7, 134-135
doi; 10.1038/nchembio.529
PMID;3513710  PMC21321551

Gilbert, I. H., Leroy, D. and Frearson, J. A. (2011) Finding new hits in neglected disease projects: target or phenotypic based screening? Curr Top Med Chem. 11, 1284-1291
doi;  PMC21401505

Gkikopoulos, T., Schofield, P., Singh, V., Pinskaya, M., Mellor, J., Smolle, M., Workman, J. L., Barton, G. J. and Owen-Hughes, T. (2011) A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization. Science. 333, 1758-1760
doi; 10.1126/science.1206097
PMID;3428865  PMC21940898

Gkikopoulos, T., Singh, V., Tsui, K., Awad, S., Renshaw, M. J., Scholfield, P., Barton, G. J., Nislow, C., Tanaka, T. U. and Owen-Hughes, T. (2011) The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4. EMBO J. 30, 1919-1927
doi; 10.1038/emboj.2011.112
PMID;3098484  PMC21505420

Gray, D. W., Breneman, S. R., Topper, L. A. and Sharkey, T. D. (2011) Biochemical Characterization and Homology Modeling of Methylbutenol Synthase and Implications for Understanding Hemiterpene Synthase Evolution in Plants. Journal of Biological Chemistry. 286, 20582-20590
doi; DOI 10.1074/jbc.M111.237438

Hampton, S. E., Baragana, B., Schipani, A., Bosch-Navarrete, C., Musso-Buendia, J. A., Recio, E., Kaiser, M., Whittingham, J. L., Roberts, S. M., Shevtsov, M., Brannigan, J. A., Kahnberg, P., Brun, R., Wilson, K. S., Gonzalez-Pacanowska, D., Johansson, N. G. and Gilbert, I. H. (2011) Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. ChemMedChem. 6, 1816-1831
doi;  PMC22049550

Hopkins, A. L., Bickerton, G. R., Carruthers, I. M., Boyer, S. K., Rubin, H. and Overington, J. P. (2011) Rapid analysis of pharmacology for infectious diseases. Curr Top Med Chem. 11, 1292-1300
PMID;3182413  PMC21401504

Hopkins, A. L. and Wyatt, P. G. (2011) Progress in Neglected Disease Drug Discovery. Current Topics in Medicinal Chemistry. 11, 1215-1215

Hunter, W. N. (2011) Isoprenoid Precursor Biosynthesis Offers Potential Targets for Drug Discovery Against Diseases Caused by Apicomplexan Parasites. Current Topics in Medicinal Chemistry. 11, 2048-2059

Kajbaf, M., Longhi, R., Montanari, D., Vinco, F., Rigo, M., Fontana, S. and Read, K. D. (2011) A comparative study of the CYP450 inhibition potential of marketed drugs using two fluorescence based assay platforms routinely used in the pharmaceutical industry. Drug Metab Lett. 5, 30-39

Konig, J., Wyllie, S., Wells, G., Stevens, M. F., Wyatt, P. G. and Fairlamb, A. H. (2011) Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism. J Biol Chem. 286, 8523-8533
doi; M110.214833 [pii]
PMID;3048735  PMC21212280

Koumandou, V. L., Klute, M. J., Herman, E. K., Nunez-Miguel, R., Dacks, J. B. and Field, M. C. (2011) Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei. J Cell Sci. 124, 1496-1509
doi; 10.1242/jcs.081596
PMID;3078816  PMC21502137

Krasowski, A., Muthas, D., Sarkar, A., Schmitt, S. and Brenk, R. (2011) DrugPred: a structure-based approach to predict protein druggability developed using an extensive nonredundant data set. J Chem Inf Model. 51, 2829-2842
doi; 10.1021/ci200266d

Lamb, D., Schuttelkopf, A. W., van Aalten, D. M. and Brighty, D. W. (2011) Charge-surrounded pockets and electrostatic interactions with small ions modulate the activity of retroviral fusion proteins. PLoS Pathog. 7, e1001268
doi; 10.1371/journal.ppat.1001268
PMID;3033372  PMC21304939

Large, C. H., Bison, S., Sartori, I., Read, K. D., Gozzi, A., Quarta, D., Antolini, M., Hollands, E., Gill, C. H., Gunthorpe, M. J., Idris, N., Neill, J. C. and Alvaro, G. S. (2011) The efficacy of sodium channel blockers to prevent phencyclidine-induced cognitive dysfunction in the rat: potential for novel treatments for schizophrenia. J Pharmacol Exp Ther. 338, 100-113
doi; 10.1124/jpet.110.178475

Lopez-Larson, M. P., Anderson, J. S., Ferguson, M. A. and Yurgelun-Todd, D. (2011) Local brain connectivity and associations with gender and age. Dev Cogn Neurosci. 1, 187-197
doi; 10.1016/j.dcn.2010.10.001
PMID;3079272  PMC21516202

Lumb, J. H., Leung, K. F., Dubois, K. N. and Field, M. C. (2011) Rab28 function in trypanosomes: interactions with retromer and ESCRT pathways. J Cell Sci. 124, 3771-3783
doi; 10.1242/jcs.079178
PMID;3225266  PMC22100919

Marino, K., Guther, M. L., Wernimont, A. K., Qiu, W., Hui, R. and Ferguson, M. A. (2011) Characterization, localization, essentiality, and high-resolution crystal structure of glucosamine 6-phosphate N-acetyltransferase from Trypanosoma brucei. Eukaryot Cell. 10, 985-997
doi; 10.1128/EC.05025-11
PMID;3147419  PMC21531872

Miller, M. H., Ferguson, M. A. and Dillon, J. F. (2011) Systematic review of performance of non-invasive biomarkers in the evaluation of non-alcoholic fatty liver disease. Liver Int. 31, 461-473
doi; 10.1111/j.1478-3231.2011.02451.x

Milner, E., Sousa, J., Pybus, B., Melendez, V., Gardner, S., Grauer, K., Moon, J., Carroll, D., Auschwitz, J., Gettayacamin, M., Lee, P., Leed, S., McCalmont, W., Norval, S., Tungtaeng, A., Zeng, Q., Kozar, M., Read, K. D., Li, Q. and Dow, G. (2011) Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum. Eur J Drug Metab Pharmacokinet. 36, 151-158
doi; 10.1007/s13318-011-0047-8

Mok, N. Y. and Brenk, R. (2011) Mining the ChEMBL database: an efficient chemoinformatics workflow for assembling an ion channel-focused screening library. J Chem Inf Model. 51, 2449-2454
doi; 10.1021/ci200260t
PMID;3200031  PMC21978256

Morgan, R. E., Batot, G. O., Dement, J. M., Rao, V. A., Eadsforth, T. C. and Hunter, W. N. (2011) Crystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroate. Bmc Structural Biology. 11doi; 21

Mutsaers, C. A., Wishart, T. M., Lamont, D. J., Riessland, M., Schreml, J., Comley, L. H., Murray, L. M., Parson, S. H., Lochmuller, H., Wirth, B., Talbot, K. and Gillingwater, T. H. (2011) Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Hum Mol Genet. 20, 4334-4344
doi; 10.1093/hmg/ddr360

Navratilova, I., Besnard, J. and Hopkins, A. L. (2011) Screening for GPCR Ligands Using Surface Plasmon Resonance. ACS Med Chem Lett. 2, 549-554
doi; 10.1021/ml2000017
PMID;3137231  PMC21765967

Navratilova, I. and Hopkins, A. L. (2011) Emerging role of surface plasmon resonance in fragment-based drug discovery. Future Med Chem. 3, 1809-1820
doi; 10.4155/fmc.11.128

Nikolaev, A. V. and Al-Maharik, N. (2011) Synthetic glycosylphosphatidylinositol (GPI) anchors: how these complex molecules have been made. Natural product reports. 28, 970-1020
doi; 10.1039/c0np00064g

Ong, H. B., Sienkiewicz, N., Wyllie, S. and Fairlamb, A. H. (2011) Dissecting the metabolic roles of pteridine reductase 1 in Trypanosoma brucei and Leishmania major. J Biol Chem. 286, 10429-10438
doi; 10.1074/jbc.M110.209593
PMID;3060496  PMC21239486

Ono, M., Scott, M. S., Yamada, K., Avolio, F., Barton, G. J. and Lamond, A. I. (2011) Identification of human miRNA precursors that resemble box C/D snoRNAs. Nucleic Acids Res. 39, 3879-3891
doi; 10.1093/nar/gkq1355
PMID;3089480  PMC21247878

Orchard, S., Al-Lazikani, B., Bryant, S., Clark, D., Calder, E., Dix, I., Engkvist, O., Forster, M., Gaulton, A., Gilson, M., Glen, R., Grigorov, M., Hammond-Kosack, K., Harland, L., Hopkins, A., Larminie, C., Lynch, N., Mann, R. K., Murray-Rust, P., Lo Piparo, E., Southan, C., Steinbeck, C., Wishart, D., Hermjakob, H., Overington, J. and Thornton, J. (2011) Minimum information about a bioactive entity (MIABE). Nat Rev Drug Discov. 10, 661-669
doi; 10.1038/nrd3503

O'Rourke, P. E., Eadsforth, T. C., Fyfe, P. K., Shepherd, S. M. and Hunter, W. N. (2011) Pseudomonas aeruginosa 4-amino-4-deoxychorismate lyase: spatial conservation of an active site tyrosine and classification of two types of enzyme. PLoS One. 6, e24158
doi; 10.1371/journal.pone.0024158
PMID;3174152  PMC21935381

Overton, I. M. and Barton, G. J. (2011) Computational approaches to selecting and optimising targets for structural biology. Methods. 55, 3-11
doi; 10.1016/j.ymeth.2011.08.014
PMID;3202631  PMC21906678

Overton, I. M., Graham, S., Gould, K. A., Hinds, J., Botting, C. H., Shirran, S., Barton, G. J. and Coote, P. J. (2011) Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus. BMC Syst Biol. 5, 68
doi; 10.1186/1752-0509-5-68
PMID;3123200  PMC21569391

Overton, I. M., van Niekerk, C. A. and Barton, G. J. (2011) XANNpred: neural nets that predict the propensity of a protein to yield diffraction-quality crystals. Proteins. 79, 1027-1033
doi; 10.1002/prot.22914
PMID;3084997  PMC21246630

Patterson, S., Alphey, M. S., Jones, D. C., Shanks, E. J., Street, I. P., Frearson, J. A., Wyatt, P. G., Gilbert, I. H. and Fairlamb, A. H. (2011) Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallography. J Med Chem. 54, 6514-6530
doi; 10.1021/jm200312v
PMID;3188286  PMC21851087

Perry, M. R., Wyllie, S., Prajapati, V. K., Feldmann, J., Sundar, S., Boelaert, M. and Fairlamb, A. H. (2011) Visceral leishmaniasis and arsenic: an ancient poison contributing to antimonial treatment failure in the Indian subcontinent? PLoS Negl Trop Dis. 5, e1227
doi; 10.1371/journal.pntd.0001227
PMID;3181240  PMC21980542

Philpott, M., Yang, J., Tumber, T., Fedorov, O., Uttarkar, S., Filippakopoulos, P., Picaud, S., Keates, T., Felletar, I., Ciulli, A., Knapp, S. and Heightman, T. D. (2011) Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery. Mol Biosyst. 7, 2899-2908
doi; 10.1039/c1mb05099k

Piorkowski, B. A., Lees, A. and Barton, G. J. (2011) Single maximal versus combination punch kinematics. Sports Biomech. 10, 1-11
doi; 10.1080/14763141.2010.547590

Rao, V. A., Shepherd, S. M., English, G., Coulthurst, S. J. and Hunter, W. N. (2011) The structure of Serratia marcescens Lip, a membrane-bound component of the type VI secretion system. Acta crystallographica. Section D, Biological crystallography. 67, 1065-1072
doi; 10.1107/S0907444911046300
PMID;3225178  PMC22120744

Rimsa, V., Eadsforth, T. and Hunter, W. N. (2011) The role of Co2+in the crystallization of human SENP1 and comments on the limitations of automated refinement protocols. Acta Crystallographica Section F-Structural Biology and Crystallization Communications. 67, 442-445
doi; 10.1107/s1744309111005835

Ryan, C. M., Mehlert, A., Richardson, J. M., Ferguson, M. A. and Johnson, P. J. (2011) Chemical structure of Trichomonas vaginalis surface lipoglycan: a role for short galactose (beta1-4/3) N-acetylglucosamine repeats in host cell interaction. J Biol Chem. 286, 40494-40508
doi; 10.1074/jbc.M111.280578
PMID;3220458  PMC21900246

Sainsbury, S., Bird, L., Rao, V., Shepherd, S. M., Stuart, D. I., Hunter, W. N., Owens, R. J. and Ren, J. (2011) Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms. J Mol Biol. 405, 173-184
doi; 10.1016/j.jmb.2010.10.024
PMID;3025346  PMC20974151

Scott, M. S., Boisvert, F. M., Lamond, A. I. and Barton, G. J. (2011) PNAC: a protein nucleolar association classifier. BMC Genomics. 12, 74
doi; 10.1186/1471-2164-12-74
PMID;3038921  PMC21272300

Scott, M. S., Troshin, P. V. and Barton, G. J. (2011) NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins. BMC Bioinformatics. 12, 317
doi; 10.1186/1471-2105-12-317
PMID;3166288  PMC21812952

Sizova, O. V., Ross, A. J., Ivanova, I. A., Borodkin, V. S., Ferguson, M. A. and Nikolaev, A. V. (2011) Probing elongating and branching beta-D-galactosyltransferase activities in Leishmania parasites by making use of synthetic phosphoglycans. ACS Chem Biol. 6, 648-657
doi; 10.1021/cb100416j
PMID;3659391  PMC21425873

Smith, V. C., Cleghorn, L. A., Woodland, A., Spinks, D., Hallyburton, I., Collie, I. T., Mok, N. Y., Norval, S., Brenk, R., Fairlamb, A. H., Frearson, J. A., Read, K. D., Gilbert, I. H. and Wyatt, P. G. (2011) Optimisation of the anti-Trypanosoma brucei activity of the opioid agonist U50488. ChemMedChem. 6, 1832-1840
doi; 10.1002/cmdc.201100278
PMID;3229842  PMC21834094

Spinks, D., Ong, H. B., Mpamhanga, C. P., Shanks, E. J., Robinson, D. A., Collie, I. T., Read, K. D., Frearson, J. A., Wyatt, P. G., Brenk, R., Fairlamb, A. H. and Gilbert, I. H. (2011) Design, synthesis and biological evaluation of novel inhibitors of Trypanosoma brucei pteridine reductase 1. ChemMedChem. 6, 302-308
doi; 10.1002/cmdc.201000450
PMID;3047710  PMC21275054

Sugden, C., Ross, S., Annesley, S. J., Cole, C., Bloomfield, G., Ivens, A., Skelton, J., Fisher, P. R., Barton, G. and Williams, J. G. (2011) A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation. Dev Biol. 353, 290-301
doi; 10.1016/j.ydbio.2011.03.003
PMID;3085826  PMC21396932

Troshin, P. V., Postis, V. L., Ashworth, D., Baldwin, S. A., McPherson, M. J. and Barton, G. J. (2011) PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities. BMC Res Notes. 4, 48
doi; 10.1186/1756-0500-4-48
PMID;3058032  PMC21385349

Troshin, P. V., Procter, J. B. and Barton, G. J. (2011) Java bioinformatics analysis web services for multiple sequence alignment--JABAWS:MSA. Bioinformatics. 27, 2001-2002
doi; 10.1093/bioinformatics/btr304
PMID;3129525  PMC21593132

Walton, J. G., Jones, D. C., Kiuru, P., Durie, A. J., Westwood, N. J. and Fairlamb, A. H. (2011) Synthesis and evaluation of indatraline-based inhibitors for trypanothione reductase. ChemMedChem. 6, 321-328
doi; 10.1002/cmdc.201000442
PMID;3047706  PMC21275055

Woodroof, H. I., Pogson, J. H., Begley, M., Cantley, L. C., Deak, M., Campbell, D. G., van Aalten, D. M., Whitworth, A. J., Alessi, D. R. and Muqit, M. M. (2011) Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations. Open Biol. 1, 110012
doi; 10.1098/rsob.110012
PMID;3352081  PMC22645651

Wyatt, P. G., Gilbert, I. H., Read, K. D. and Fairlamb, A. H. (2011) Target validation: linking target and chemical properties to desired product profile. Curr Top Med Chem. 11, 1275-1283
doi; PMID;3182078  PMC21401506

Wyllie, S. and Fairlamb, A. H. (2011) Methylglyoxal metabolism in trypanosomes and leishmania. Semin Cell Dev Biol. 22, 271-277
doi; S1084-9521(11)00014-0 [pii]
PMID;3107426  PMC21310261