University of Dundee

Molecular Medicine 2011

Brown, S. J., Asai, Y., Cordell, H. J., Campbell, L. E., Zhao, Y. W., Liao, H. H., Northstone, K., Henderson, J., Alizadehfar, R., Ben-Shoshan, M., Morgan, K., Roberts, G., Masthoff, L. J. N., Pasmans, S., van den Akker, P. C., Wijmenga, C., Hourihane, J. O., Palmer, C. N. A., Lack, G., Clarke, A., Hull, P. R., Irvine, A. D. and McLean, W. H. I. Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy. Journal of Allergy and Clinical Immunology, 127, 661-667. PMID: 21377035

Chen, H., J. E. Common, et al. (2011). "Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations." The British Journal of Dermatology 165(1): 106-114.

Clericuzio, C., Harutyunyan, K., Jin, W., Erickson, R. P., Irvine, A. D., McLean, W. H. I., Wen, Y., Bagatell, R., Griffin, T. A., Shwayder, T. A., Plon, S. E. and Wang, L. L. Identification of a Novel C16orf57 Mutation in Athabaskan Patients With Poikiloderma With Neutropenia. American Journal of Medical Genetics, 155A. PMID: 21271650

Gruber, R., P. M. Elias, et al. (2011). "Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function." The American Journal of Pathology 178(5): 2252-2263.

Hickerson, R. P., S. A. Leachman, et al. (2011). "Development of quantitative molecular clinical end points for siRNA clinical trials." The Journal of Investigative Dermatology 131(5): 1029-1036.

Jakasa, I., Koster, E. S., Calkoen, F., McLean, W. H. I., Campbell, L. E., Bos, J. D., Verberk, M. M. and Kezic, S. Skin Barrier Function in Healthy Subjects and Patients with Atopic Dermatitis in Relation to Filaggrin Loss-of-Function Mutations. Journal of Investigative Dermatology, 131, 540-542. PMID: 20962854

Kaspar, R. L., S. A. Leachman, et al. (2011). "Toward a treatment for pachyonychia congenita: report on the 7th Annual International Pachyonychia Congenita Consortium meeting." The Journal of Investigative Dermatology 131(5): 1011-1014.

Margolis, D. J., M. Papadopoulos, et al. (2011). "Obtaining DNA in the mail from a national sample of children with a chronic non-fatal illness." The Journal of Investigative Dermatology 131(8): 1765-1767.

McLean, W. H. (2011). "The allergy gene: how a mutation in a skin protein revealed a link between eczema and asthma." F1000 medicine reports 3: 2.

McLean, W. H. I., C. D. Hansen, et al. (2011). "The Phenotypic and Molecular Genetic Features of Pachyonychia Congenita." Journal of Investigative Dermatology 131(5): 1015-1017.

Wilson, N. J., S. A. Leachman, et al. (2011). "A large mutational study in pachyonychia congenita." The Journal of Investigative Dermatology 131(5): 1018-1024.

Zhao, Y. W., U. Gartner, et al. (2011). "Statins Downregulate K6a Promoter Activity: A Possible Therapeutic Avenue for Pachyonychia Congenita." Journal of Investigative Dermatology 131(5): 1045-1052.