University of Dundee

Molecular Physiology 2009

Babraj, J. A., Mustard, K., Sutherland, C., Towler, M. C., Chen, S., Smith, K., Green, K., Leese, G., Hardie, D. G., Rennie, M. J. and Cuthbertson, D. J. (2009) Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status. American Journal of Physiology-Endocrinology and Metabolism. 296, E1042-E1048

Baird, F. E., Bett, K. J., MacLean, C., Tee, A. R., Hundal, H. S. and Taylor, P. M. (2009) Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes. American Journal of Physiology-Endocrinology and Metabolism. 297, E822-E829

Bendayan, M., Londono, I., Kemp, B. E., Hardie, G. D., Ruderman, N. and Prentki, M. (2009) Association of AMP-activated Protein Kinase Subunits With Glycogen Particles as Revealed In Situ by Immunoelectron Microscopy. Journal of Histochemistry & Cytochemistry. 57, 963-971

Beyer, S. R., Mallmann, R., Habermeier, A., Taylor, P. M., Boissel, J. P. and Closs, E. I. (2009) Two cysteine residues in the human cationic amino acid transporter hCAT-2A are necessary for its inhibition by N-ethylmaleimide (NEM). Naunyn-Schmiedebergs Archives of Pharmacology. 379, 3

Cao, J. X., Schulte, J., Knight, A., Leslie, N. R., Zagozdzon, A., Bronson, R., Manevich, Y., Beeson, C. and Neumann, C. A. (2009) Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. Embo Journal. 28, 1505-1517

Dallas, M. L., Scragg, J. L., Wyatt, C. N., Ross, F., Hardie, D. G., Evans, A. M. and Peers, C. (2009) Modulation of O-2 Sensitive K+ Channels by AMP-activated Protein Kinase. Arterial Chemoreceptors. 648, 57-63

Dyavanapalli, J., Rimmer, K. and Harper, A. A. (2009) The action of high K+ and aglycaemia on the electrical properties and synaptic transmission in rat intracardiac ganglion neurones in vitro. Experimental Physiology. 94, 201-212

Evans, A. M., Hardie, D. G., Peers, C., Wyatt, C. N., Viollet, B., Kumar, P., Dallas, M. L., Ross, F., Ikematsu, N., Jordan, H. L., Barr, B. L., Rafferty, J. N. and Ogunbayo, O. (2009) Ion Channel Regulation by AMPK The Route of Hypoxia-Response Coupling in the Carotid Body and Pulmonary Artery. Hypoxia and Consequences from Molecule to Malady. 1177, 89-100

Evans, A. M., Peers, C. and Hardie, D. G. (2009) AMP-ACTIVATED PROTEIN KINASE MONITORS RESPIRATORY GASES AS AN INDEX OF RESPIRATORY FUNCTION AND ENERGY SUPPLY AT THE WHOLE-BODY LEVEL. Journal of Physiological Sciences. 59, 405-405

Fogarty, S. and Hardie, D. G. (2009) C-terminal Phosphorylation of LKB1 Is Not Required for Regulation of AMP-activated Protein Kinase, BRSK1, BRSK2, or Cell Cycle Arrest. Journal of Biological Chemistry. 284, 77-84

Hadad, S. M., Baker, L., Quinlan, P. R., Robertson, K. E., Bray, S. E., Thomson, G., Kellock, D., Jordan, L. B., Purdie, C. A., Hardie, D. G., Fleming, S. and Thompson, A. M. (2009) Histological evaluation of AMPK signalling in primary breast cancer. Bmc Cancer. 9

Hardie, D. G. and McBride, A. (2009) SENSING OF ENERGY AVAILABILITY BY THE AMP-ACTIVATED PROTEIN KINASE. Journal of Physiological Sciences. 59, 61-61

Hundal, H., Cwiklinski, E. and Taylor, P. M. (2009) Sensing and signaling functions associated with the SNAT2 amino acid transporter. Amino Acids. 37, 8-8

Hundal, H. S. and Taylor, P. M. (2009) Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling. American Journal of Physiology-Endocrinology and Metabolism. 296, E603-E613

Leslie, N. R., Maccario, H., Spinelli, L. and Davidson, L. (2009) The significance of PTEN's protein phosphatase activity. Advances in Enzyme Regulation, Vol 49. 49, 190-196

MacKenzie, M. G., Hamilton, D. L., Murray, J. T., Taylor, P. M. and Baar, K. (2009) mVps34 is activated following high-resistance contractions. Journal of Physiology-London. 587, 253-260

McBride, A., Ghilagaber, S., Nikolaev, A. and Hardie, D. G. (2009) The Glycogen-Binding Domain on the AMPK beta Subunit Allows the Kinase to Act as a Glycogen Sensor. Cell Metabolism. 9, 23-34

McBride, A. and Hardie, D. G. (2009) AMP-activated protein kinase - a sensor of glycogen as well as AMP and ATP? Acta Physiologica. 196, 99-113

Paytubi, S., Wang, X. M., Lam, Y. W., Izquierdo, L., Hunter, M. J., Jan, E., Hundal, H. S. and Proud, C. G. (2009) ABC50 Promotes Translation Initiation in Mammalian Cells. Journal of Biological Chemistry. 284, 24061-24073

Pehmoller, C., Treebak, J. T., Birk, J. B., Chen, S., MacKintosh, C., Hardie, D. G., Richter, E. A. and Wojtaszewski, J. F. P. (2009) Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle. American Journal of Physiology-Endocrinology and Metabolism. 297, E665-E675

Ramel, D., Lagarrigue, F., Dupuis-Coronas, S., Chicanne, G., Leslie, N., Gaits-Iacovoni, F., Payrastre, B. and Tronchere, H. (2009) PtdIns5P protects Akt from dephosphorylation through PP2A inhibition. Biochemical and Biophysical Research Communications. 387, 127-131

Stretton, C., Litherland, G. J., Moynihan, A., Hajduch, E. and Hundal, H. S. (2009) Expression and modulation of TUB by insulin and thyroid hormone in primary rat and murine 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications. 390, 1328-1333

Stretton, C., Litherland, G. J., Moynihan, A., Hajduch, E. and Hundal, H. S. (2009) Expression and modulation of TUB by insulin and thyroid hormone in primary rat and murine 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications. 390

Taylor, P. M. (2009) Amino acid transporters: eminences grises of nutrient signalling mechanisms? Biochemical Society Transactions. 37, 237-241

Treebak, J. T., Frosig, C., Pehmoller, C., Chen, S., Maarbjerg, S. J., Brandt, N., MacKintosh, C., Zierath, J. R., Hardie, D. G., Kiens, B., Richter, E. A., Pilegaard, H. and Wojtaszewski, J. F. P. (2009) Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle. Diabetologia. 52, 891-900

Tuupanen, S., Turunen, M., Lehtonen, R., Hallikas, O., Vanharanta, S., Kivioja, T., Bjorklund, M., Wei, G. H., Yan, J., Niittymaki, I., Mecklin, J. P., Jarvinen, H., Ristimaki, A., Di-Bernardo, M., East, P., Carvajal-Carmona, L., Houlston, R. S., Tomlinson, I., Palin, K., Ukkonen, E., Karhu, A., Taipale, J. and Aaltonen, L. A. (2009) The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nature Genetics. 41, 885-U837

van Diepen, M. T., Parsons, M., Downes, C. P., Leslie, N. R., Hindges, R. and Eickholt, B. J. (2009) MyosinV controls PTEN function and neuronal cell size. Nature Cell Biology. 11, 1191-U1155

Watson, M. L., Coghlan, M. and Hundal, H. S. (2009) Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells. Biochemical Journal. 417, 791-801

Whyte, K. A., Hogg, R. C., Dyavanapalli, J., Harper, A. A. and Adams, D. J. (2009) Reactive oxygen species modulate neuronal excitability in rat intrinsic cardiac ganglia. Autonomic Neuroscience-Basic & Clinical. 150, 45-52