University of Dundee

Wellcome 4-Year PhD Programme in Integrated Molecular, Cellular and Translational Biology

The Wellcome Trust Integrated molecular, cellular and translational biology programme combines scientific excellence with a commitment to improving the working environment and transition support for trainees. This PhD programme, provided by world-renowned scientists from the School of Life Sciences at the University of Dundee, will train the next generation of scientists at the forefront of international science. Students will join our supportive and positive research culture with the opportunity to select research projects centred around four themes:

  1. Cellular Regulation
  2. Protein Modification
  3. Infection and Immunity
  4. Drug Discovery and Translation

Around 50 different potential supervisors will participate in this programme 

Dr Edgar Huitema

Our lab aims to understand the mechanisms by which P. capsici achieves virulence on and ravages multiple crops. Our research is guided by the observation that secreted molecules (effectors) from Phytophthora, play pivotal roles in disease establishment and epidemics. Genome sequences for an increasing number of distinct Phytophthora species now allows us to define the Phytophthora repertoires required for infection and host range. We are interested in the functional roles of effectors in epidemics and the factors that control their expression.  With the new understanding about the role of effector proteins during disease and the availability of P. capsici genome sequences, we aim to study and perturb the pathways that control effector gene expression, delivery and their activities. Knowledge gleaned from this dynamic parasite will help us disable pathogenesis and control disease.The development of novel control methods that limits epidemics will help reduce P. capsici incited economic losses and improve disease management strategies of other oomycetes.