University of Dundee

Wellcome 4-Year PhD Programme in Integrated Molecular, Cellular and Translational Biology

The Wellcome Trust Integrated molecular, cellular and translational biology programme combines scientific excellence with a commitment to improving the working environment and transition support for trainees. This PhD programme, provided by world-renowned scientists from the School of Life Sciences at the University of Dundee, will train the next generation of scientists at the forefront of international science. Students will join our supportive and positive research culture with the opportunity to select research projects centred around four themes:

  1. Cellular Regulation
  2. Protein Modification
  3. Infection and Immunity
  4. Drug Discovery and Translation

Around 50 different potential supervisors will participate in this programme


Prof Daan van Aalten

Ogt encodes an essential enzyme, the O-GlcNAc transferase, that catalyses an abundant nucleocytoplasmic post-transcriptional modification called O-GlcNAcylation and is mutated in several families with intellectual disability. In the van Aalten lab we use a wide range  of techniques to study the effects of these mutations,  ranging from chemical biology, biochemistry, molecular biology, cell biology and genetics, in stem cells, flies and mice. The aim of the lab is to uncover the links between O-GlcNAcylation and the patient phenotypes and explore pharmaceutical/genetic approaches to treating these