Professor Karim Labib FRSE
Research
Publications
Top Ten Publications
Deegan, T.D., Baxter, J., Ortiz-Bazan, M.A., Yeeles, T.P. and Labib, K.P.M. (2019) Pif1-family helicases support fork convergence during DNA replication termination in eukaryotes. Mol Cell, 18, 231-244.
Mukherjee, P.P. and Labib, K.P.M. (2019) In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-dependent Disassembly of the CMG helicase in Budding Yeast. Cell Rep., 28, 2777-2783
Deng L, Wu RA, Sonneville R, Kochenova OV, Labib K, Pellman D, Walter JC. (2019) Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. Mol Cell, 73, 915-929
Evrin C, Maman JD, Diamante A, Pellegrini L, Labib K. (2018) Histone H2A-H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin. EMBO J., 37, pii: e99021. doi: 10.15252/embj.201899021
Sonneville R, Moreno SP, Knebel A, Johnson C, Hastie CJ, Gartner A, Gambus A, Labib K. (2017) CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis. Nat. Cell Biol., 19, 468-479.
Maric M, Mukherjee P, Tatham MH, Hay R, Labib K. (2017) Ufd1-Npl4 Recruit Cdc48 for Disassembly of Ubiquitylated CMG Helicase at the End of Chromosome Replication. Cell Rep. 18, 3033-3042.