25 Sep 2020
Researchers at the University of Dundee are looking to transform pharmaceutical and cosmetics testing with their spinout venture that offers an alternative for many experiments currently only performed in animals.
17 Sep 2020
The finalists for Converge 2020, Scotland’s leading academic company creation programme, have been announced with representation from the School included on the list with Dr Robyn Hickerson, Co-founder and Chief Scientific Officer of Ten Bio.
15 Sep 2020
An article by Julia Wcislo is one of the ten outstanding articles that have been shortlisted for the 2020 Max Perutz Science Writing Award, the MRC’s annual writing competition.
10 Sep 2020
The annual Times Higher Education Awards shortlist was announced this morning with the School having representation in three categories. David Martin for Most Innovative Teacher of the Year; Bill Hunter for Outstanding Research Supervisor of the Year; and the Division of Signal Transduction Therapy (DSTT) for Knowledge Exchange/Transfer Initiative of the Year.
15 Jul 2020
University of Dundee researchers have demonstrated a new method of destroying an ‘undruggable’ protein known to play a role in cancer, raising the possibility of a new therapeutic approach to the disease. Mutations of the K-Ras protein have long been known to cause many cancers, including lung, colorectal, and pancreatic cancers, but despite decades of work by researchers across the world, an inhibitor for this protein has proven elusive. As a result, scientists have increasingly looked to novel ways of targeting K-Ras.
02 Jul 2020
During lockdown, the School of Life Sciences at the University of Dundee was not closed. Work continued albeit on a much smaller scale than usual, with the majority of the ongoing research focussed on coronavirus. Our support staff were absolutely critical in keeping the research complex functioning to allow this important work to happen. As we have entered phase 2 of the Scottish Government’s route map out of lockdown, we look back over the past few months and the challenges that our community in the School encountered and had to overcome.
08 Jun 2020
Almost twenty years after deciphering the human genome, our understanding of human disease is still far from complete. One of the most powerful and versatile tools to better understand biology and disease-relevant processes are well-characterized small chemical modulators of protein function. The newly formed public-private partnership “Enabling and Unlocking biology in the OPEN” (EUbOPEN) aims to develop high quality chemical tool compounds for 1,000 proteins (one third of the druggable proteins in the human body).
18 May 2020
Proteolysis-targeting chimera (PROTAC) compounds developed at the University of Dundee are being made available free of charge by the pharmaceutical company Boehringer Ingelheim through their scientific crowdsourcing platform opnMe.com. The opnMe portal provides free and open access to selected molecules for the scientific community aiming at accelerating research initiatives that can benefit patients with high unmet medical need.
28 Apr 2020
Back in October 2013 Medicines for Malaria Venture (MMV) selected a compound designed and developed at the Drug Discovery Unit (DDU), University of Dundee to enter preclinical development. In June 2015, the discovery, properties and mode of action of the compound DDD107498 were published in the journal Nature.
16 Apr 2020
The University of Dundee is working with partners around the world as part of an expanding effort to rapidly repurpose existing drugs against Covid-19. An international research network established by Scripps Research centres around ReFRAME, the world’s leading collection of drugs known to be safe in humans. The network of collaborating scientific laboratories is aiming to leverage ReFRAME to find antiviral compounds against the novel coronavirus.