13 May 2020
Researchers within the Reagents and Services division of the MRC PPU and the MRC-University of Glasgow Centre for Virus Research (CVR) have worked extremely hard since January in order to produce expression plasmids, proteins and sheep affinity purified polyclonal antibodies to all 28 proteins encoded for by SARS-CoV-2. In addition, they have generated equivalent reagents to 10 other proteins from related Coronaviruses.
12 May 2020
Launching today, Tuesday 12 May, the COVID-19 Protein Portal allows UK scientists to access protein reagents for critical research relating to SARS-CoV-2. Protein reagents are provided free of charge by a consortium of leading protein production laboratories, in an Open Science initiative led by Wellcome and UKRI.
23 Apr 2020
Despite the coronavirus lockdown, researchers from MRC PPU are continuing to attend online meetings, seminars and conferences to share ideas with researchers around the world. Last week, Nicola Darling, a postdoctoral researcher in Philip Cohen’s lab, moderated the Health and Sustainable Development session at the Third Central Asian Research Forum on Sustainable Development and Innovation that involved researchers based in or from Kazakhstan.
06 Apr 2020
University of Dundee researchers are studying a protein that aids the spread of COVID-19 in the hope of finding ways of blocking its function. The team, from the University’s Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) are working in partnership with the Drug Discovery Unit (DDU) to study an enzyme found within the SARS-CoV-2 virus that causes COVID-19 infection.
MRC-PPU researchers uncover potential cross-talk between signalling pathways linked to Parkinson’s...02 Apr 2020
Researchers from the MRC-PPU have uncovered potential cross-talk between PINK1 and LRRK2 signalling pathways linked to Parkinson’s disease. This work, led by Professor Miratul Muqit and his team, was published this week in the Biochemical Journal.
30 Mar 2020
Scientists at the Universities of Dundee and Glasgow are combining their expertise to aid the global battle against coronavirus. The collaboration brings together world-leading researchers at Medical Research Council-funded units at both institutions to generate biological tools that will enable them to study the virus and identify ways of defeating it.
26 Mar 2020
A protocol for utilizing human peripheral blood neutrophils for research into the Parkinson’s disease associated LRRK2 kinase has been published. The collaborative work led by Esther Sammler, Clinical Programme Leader in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit in the School and Clinical Senior Lecturer & Honorary Consultant in the School of Medicine.
13 Mar 2020
New research by Greg Findlay’s group in the MRC-PPU has identified a signalling system that controls embryonic stem cell development, which has implications for understanding how tissues form within the mammalian embryo. The paper, by Rosalia Fernandez-Alonso and Francisco Bustos, post-doctoral investigators in Greg’s lab, uncovers a new role for the EPH-Ephrin system in regulating stem cell differentiation.
03 Mar 2020
Two Life Sciences academics who are helping transform lives with their work on major diseases including Parkinson’s and neglected tropical diseases such as malaria have been elected Fellows of the Royal Society of Edinburgh (RSE). The RSE is Scotland’s national academy, focused on delivering its mission of `knowledge made useful’. Fellows are elected in recognition of their impact in improving the world around them.
New collaboration will harness latest technology to uncover role of proteins in neurodegenerative...02 Mar 2020
A pioneering collaboration between the UK Dementia Research Institute (DRI) and the Medical Research Council’s Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) will use the very latest advances in technology to study rare cell populations and the role of proteins in diseases such as Alzheimer’s and Parkinson’s.