University of Dundee

Latest News for 10/2021

February 2016

August 2015

  • 05 Aug 2015

    A mechanism that is responsible for the drug susceptibility of parasites that cause devastating diseases, known as nagana in cattle and sleeping sickness in humans, has been identified for the first time in a research breakthrough led by the University of Dundee.   African trypanosomiasis is an infection affecting both animals and humans. It can have a devastating impact, particularly in rural areas, and is the most economically important livestock disease in Africa, where it is known as `nagana’.

November 2013

  • 29 Nov 2013

    Researchers from David Horn's lab working with colleagues at the University of Sussex, have made a breakthrough in our understanding of how enzymes that make DNA, complete genome replication. Scientists studied a pair of primase polymerase-like (PPL) enzymes in the African trypanosome, a protozoan parasite that causes important diseases of humans and animals. These enzymes are also found in mammalian cells and many other eukaryotes.

  • 26 Nov 2013

    Scientists at the Universities of Dundee and Glasgow have discovered how drugs that have been used for 60 years to kill the parasite that causes sleeping sickness actually work. Research has revealed that the drugs used to attack Trypanosoma brucei enter through pores in the parasite’s cells known as aquaporins which function as water channels. It is the first time that drugs have been shown to enter cells through aquaporins and this may have major implications for drug delivery in other diseases.