University of Dundee

Latest News for 08/2022

January 2022

  • Left: Current lab members Hina Ojha and Olawale Raimi who co-led the work. Right: AlphaFold model of human PINK1.
    20 Jan 2022

    Mutations in PINK1 are the second most frequent cause of autosomal recessive early-onset Parkinson’s disease. PINK1 is activated upon mitochondrial damage to phosphorylate Ubiquitin and Parkin to stimulate Parkin E3 ligase activity, and this is critical for removal of damaged mitochondria by autophagy (mitophagy).

November 2021

  • Professor Miratul Muqit
    12 Nov 2021

    Scientists at the University of Dundee and Harvard Medical School have identified the key targets of an enzyme that play a critical role in protecting the brain against the development of Parkinson’s disease. Parkinson’s disease is the fastest growing degenerative disorder of the brain. Patients develop involuntary movements and increasing disability. To date there is no cure or treatments that can slow the disease course.

March 2021

  • Ageing Society
    11 Mar 2021

    The impact that an ageing population has on the health and wellbeing of individuals, groups, communities and societies, and what we can do to address these challenges, will be the focus of a University of Dundee lecture.

January 2021

  • LRRK2 Toolkit website homepage
    05 Jan 2021

    To help support worldwide research on LRRK2 biology, the groups of Dario Alessi and Miratul Muqit (University of Dundee) Suzanne Pfeffer and Monther Abu-Remaileh (Stanford University) have generated an LRRK2 Toolkit website in which all of their cDNA clones, antibodies, proteins, cell lines and mouse models are deposited.  

September 2020

  • Dario Alessi and Miratul Muqit
    16 Sep 2020

    A multi-million dollar research award is the “opportunity of a lifetime” to increase our understanding of Parkinson’s disease, according to a University of Dundee expert. Professor Dario Alessi says that the $9 million, three-year award from the Aligning Science Across Parkinson’s (ASAP) initiative will have a transformative impact on Parkinson’s research at the University and the quest to develop new therapies and treatments.

April 2020

March 2020

  • Professor Ian Gilbert and Professor Miratul Muqit
    03 Mar 2020

    Two Life Sciences academics who are helping transform lives with their work on major diseases including Parkinson’s and neglected tropical diseases such as malaria have been elected Fellows of the Royal Society of Edinburgh (RSE). The RSE is Scotland’s national academy, focused on delivering its mission of `knowledge made useful’. Fellows are elected in recognition of their impact in improving the world around them.

January 2020

  • School Prize Winners 2020
    15 Jan 2020

    Review of the Year 2019 took place today with the Dean, Julian Blow sharing the highlights of activity within the School from 2019. The presentation closed with the annual School prizes presentation. Here are the winners: Innovator of the Year Innovator of the Year is for any member or team within SLS that demonstrably achieved scientific, technical or commercial innovation that came to fruition in 2019.

November 2018

  • Professor Miratul Muqit
    07 Nov 2018

    Scientists in the School have confirmed that a key cellular pathway that protects the brain from damage is disrupted in Parkinson’s patients, raising the possibility of new treatments for the disease. Parkinson’s is a disabling disorder of the brain for which there is no cure. Mutations in two genes called PINK1 and Parkin are associated with early-onset forms of Parkinson’s. Both encode distinct classes of enzymes that play a pivotal role in protecting the brain against stress.

October 2018