Latest News for 08/2022
20 Jan 2022
Mutations in PINK1 are the second most frequent cause of autosomal recessive early-onset Parkinson’s disease. PINK1 is activated upon mitochondrial damage to phosphorylate Ubiquitin and Parkin to stimulate Parkin E3 ligase activity, and this is critical for removal of damaged mitochondria by autophagy (mitophagy).
12 Nov 2021
Scientists at the University of Dundee and Harvard Medical School have identified the key targets of an enzyme that play a critical role in protecting the brain against the development of Parkinson’s disease. Parkinson’s disease is the fastest growing degenerative disorder of the brain. Patients develop involuntary movements and increasing disability. To date there is no cure or treatments that can slow the disease course.
11 Mar 2021
The impact that an ageing population has on the health and wellbeing of individuals, groups, communities and societies, and what we can do to address these challenges, will be the focus of a University of Dundee lecture.
05 Jan 2021
To help support worldwide research on LRRK2 biology, the groups of Dario Alessi and Miratul Muqit (University of Dundee) Suzanne Pfeffer and Monther Abu-Remaileh (Stanford University) have generated an LRRK2 Toolkit website in which all of their cDNA clones, antibodies, proteins, cell lines and mouse models are deposited.
16 Sep 2020
A multi-million dollar research award is the “opportunity of a lifetime” to increase our understanding of Parkinson’s disease, according to a University of Dundee expert. Professor Dario Alessi says that the $9 million, three-year award from the Aligning Science Across Parkinson’s (ASAP) initiative will have a transformative impact on Parkinson’s research at the University and the quest to develop new therapies and treatments.
MRC-PPU researchers uncover potential cross-talk between signalling pathways linked to Parkinson’s...02 Apr 2020
Researchers from the MRC-PPU have uncovered potential cross-talk between PINK1 and LRRK2 signalling pathways linked to Parkinson’s disease. This work, led by Professor Miratul Muqit and his team, was published this week in the Biochemical Journal.
03 Mar 2020
Two Life Sciences academics who are helping transform lives with their work on major diseases including Parkinson’s and neglected tropical diseases such as malaria have been elected Fellows of the Royal Society of Edinburgh (RSE). The RSE is Scotland’s national academy, focused on delivering its mission of `knowledge made useful’. Fellows are elected in recognition of their impact in improving the world around them.
15 Jan 2020
Review of the Year 2019 took place today with the Dean, Julian Blow sharing the highlights of activity within the School from 2019. The presentation closed with the annual School prizes presentation. Here are the winners: Innovator of the Year Innovator of the Year is for any member or team within SLS that demonstrably achieved scientific, technical or commercial innovation that came to fruition in 2019.
07 Nov 2018
Scientists in the School have confirmed that a key cellular pathway that protects the brain from damage is disrupted in Parkinson’s patients, raising the possibility of new treatments for the disease. Parkinson’s is a disabling disorder of the brain for which there is no cure. Mutations in two genes called PINK1 and Parkin are associated with early-onset forms of Parkinson’s. Both encode distinct classes of enzymes that play a pivotal role in protecting the brain against stress.
23 Oct 2018
Kim Dale and Miratul Muqit have been promoted to Personal Chair (Professor) as part of the 2018 Annual Review process for academic staff.