University of Dundee

Wellcome Trust grant supports new tools for imaging development, aging and disease

13 Jun 2013

Researchers at the College of Life Sciences have been awarded a Wellcome Trust Grant to further build on the College’s success as an international centre of excellence in the fields of developmental and cell biology. The £800,000 multi-user equipment grant supports the purchase of a multi-photon laser-scanning microscope especially suited for development of cutting edge tissue imaging approaches.

The grant was awarded to Professors Kate Storey, Kees Weijer, Inke Näthke and Dr. Arno Müller, in the College’s Division of Cell & Developmental Biology, to support development of live tissue imaging capabilities.

Professor Kate Storey, Head of the Division of Cell and Developmental Biology, said, “live tissue imaging approaches allow analysis of key cell processes, such as division and movement in 4 dimensions and in near normal physiological conditions. This will help us to understand how embryos are built and how tissues age and change in disease states. Our approaches will also identify tissue level responses to drug treatments and other therapeutic approaches.”

The grant enables an expansion of the College’s Imaging Center to include a purpose built Tissue Imaging Centre with the College’s Light Microscopy Facility is an established, world-leading resource and already hosts some of the most advanced imaging technologies in the UK, including Electron Microscopy, Super Resolution Light Microcopy and a range of advanced light microscopes for biological imaging, which is available to a wide range of scientists within the University of Dundee and from other leading institutes. Technology within the Tissue Imaging Centre will also be accessed by a large number of researchers at the College, allowing for cross-disciplinary collaborations in a number of scientific fields.

Dr. Sam Swift, manager of the Imaging Facility, said “Over the past 10 years, the College of Life Sciences’ Imaging Centre has benefited from significant investment, providing research scientists access to a wide range of leading edge instrumentation for the study of cell biology and it is important to keep developing our technical approaches to deliver cutting edge research.

This grant also includes salary costs for staff who will maintain the microscope and advise and train users in tissue imaging.