The Ferguson Lab

PARASITE GLYCOBIOLOGY & ANTI-PARASITE DRUG DISCOVERY

2014

Capes, A.S., Crossman, A., Urbaniak, M.D., Gilbert, S.H., Ferguson, M.A. and Gilbert, I.H. (2014) "Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues". Organic and Biomolecular Chemistry 12, 1919-1934

Damerow, M. Rodrigues, J.A., Wu, D., Guther, M.L., Mehlert, A. and Ferguson, M.A. (2014) "Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei". Journal of Biological Chemistry 289, 9328-9239

Fleming, J.R., Sastry, L., Crozier, T.W.M., Napier, G.B., Sullivan, L. and Ferguson, M.A.J. (2014) Proteomic selection of immunodiagnostic antigens for Trypanosoma congolense. PLoS Neglected Tropical Disease, 6, e2936

Güther, M.L., Urbaniak, M.D., Tavendale, A., Prescott, A. and Ferguson, M.A. (2014) "High-Confidence Glycosome Proteome for Procyclic Form Trypanosoma brucei by Epitope-Tag Organelle Enrichment and SILAC Proteomics". Journal of Proteome Research, 13, 2796-2806

Izquierdo, L., Acosta-Serrano, A., Mehlert, A. and Ferguson, M.A.J. (2014) "Identification of a glycosylphosphatidylinositol anchor-modifying ß1-3 galactosyltransferase in Trypanosoma brucei". Glycobiology in press

Miller, M., Walsh, S., Atrih, A., Huang, J.T., Ferguson, M.A. and Dillon, J.F. (2014) "The Serum Proteome of Non-Alcoholic Fatty Liver Disease - A multimodal approach to discovery of biomarkers of Non-Alcoholic Steatohepatitis". Journal of Gastroenterology and Hepatology, 10, 1839-1847

Nakanishi, M., Karadusani, M., Shiraishi, T., Hashida, K., Hino, M., Ferguson, M.A. and Nomoto, H. (2014) "TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei". Parasitology International 63, 513-518

Sullivan, L., Fleming, J. Sastry, L.  Mehlert, A., Wall, S.J. and Ferguson, M.A.J. (2014) Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human African trypanosomiasis. PLoS Neglected Tropical Disease 8, e2976

Urbaniak, M.D., Capes, A.S., Crossman, A., O'Neill, S., Thompson, S., Gilbert, I.H. and Ferguson, M.A. (2014) "Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase". Carbohydrate Research 387, 54-58