Edgar Huitema

Division of Plant Sciences

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Andrew Howden

I’m a plant molecular biologist with an interest in plant signal transduction and the mechanisms by which plants respond to their environment. I’m especially interested in the use of protein biochemistry and proteomics to examine plant-microbe interactions.

As an undergraduate I studied plant sciences at the University of Edinburgh and the University of California, Davis. I then worked for one year in the lab of Professor Pam Ronald at UC Davis in order to gain some plant-microbe experience. In 2003 I began my PhD with Dr Gail Preston in Oxford where I studied the role of nitrilase enzymes in plant-associated Pseudomonas. After my PhD I worked with Dr Lee Sweetlove in Oxford studying changes in the phosphorylation of proteins during plant stress responses. I stayed in Oxford and in June 2010 I began a short project with Professor Oreste Acuto, where I used stable isotope labelling and mass spectrometry to examine changes in the proteome of human T-cells upon activation of the immune response.

I joined the Huitema lab in April 2011 where I am examining the host nuclear proteome during infection with Phytophthora capsici. Using nuclear enrichment and quantitative label-free proteomics I am interested in identifying Phytophthora-induced changes in host nuclear proteins, with the aim of understanding how this pathogen manipulates the host during infection. This may allow us to identify plant proteins that may be modified for enhanced disease resistance.

Post-Doctoral Researcher
andrew