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Ciulli Laboratory

School of Life Sciences, University of Dundee

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    • Targeted Protein Degradation: PROTACs
    • Cullin RING E3 Ubiquitin Ligases
    • Chromatin-Reader Domains
    • Fragment-Based Ligand Discovery
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News

June 2019

  • The article's joint co-authors: Sarath Ramachandran, Wei-Wei Kung and Nikolai Makukhin
    Ciulli Lab reveals how the E3 ligase SOCS2 latches on to its protein substrates

May 2019

  • Nino
    Welcome to Joachim Broeker (aka Nino) who joins the group as a visiting scientist from Boehringer Ingelheim
  • celebration 1
    Congratulations to Guilherme for successfully defending his PhD thesis viva today!

April 2019

  • ToC graphics
    Our collaboration with Dario Alessi's Lab on deploying improved HaloPROTACs against CRISPR'ed halo-tagged endosomal proteins is now out in ACS Chem Biol
  • C&EN webinar
    Will delivers a Targeted Protein Degradation Webinar with C&EN
  • Welcome to Daniela who starts as a visiting PhD student from Universita' La Sapienza (Rome, Italy)

March 2019

  • Protein slayers
    Dundee scientist front and centre of the PROTAC revolution

February 2019

  • ToC graphics
    CRBN versus VHL: our new PROTAC paper on hijacking E3 ligases against each others is now published in Bioorg. Med. Chem.
  • Wojciech 'Jay' Stec
    Welcome to Jay who starts as new postdoc in the group
  • ToC graphics
    Our new paper describing an SPR kinetic assay to monitor PROTAC ternary complexes is now out in ACS Chemical Biology

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Prof Alessio Ciulli
Professor of Chemical and Structural Biology
School of Life Sciences, University of Dundee
Division of Biological Chemistry & Drug Discovery
1 James Lindsay Place
Dundee
DD1 5JJ
United Kingdom

E-mail: a.ciulli@dundee.ac.uk
Tel: +44 (0)1382 386230
Fax: +44 (0)1382 386373

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