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Ciulli Laboratory
School of Life Sciences, University of Dundee
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Alessio Ciulli
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Alessio Ciulli
Research
Targeted Protein Degradation: PROTACs
Cullin RING E3 Ubiquitin Ligases
Chromatin-Reader Domains
Fragment-Based Ligand Discovery
Chemical Probes
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June 2019
Ciulli Lab reveals how the E3 ligase SOCS2 latches on to its protein substrates
May 2019
Welcome to Joachim Broeker (aka Nino) who joins the group as a visiting scientist from Boehringer Ingelheim
Congratulations to Guilherme for successfully defending his PhD thesis viva today!
April 2019
Our collaboration with Dario Alessi's Lab on deploying improved HaloPROTACs against CRISPR'ed halo-tagged endosomal proteins is now out in ACS Chem Biol
Will delivers a Targeted Protein Degradation Webinar with C&EN
Welcome to Daniela who starts as a visiting PhD student from Universita' La Sapienza (Rome, Italy)
March 2019
Dundee scientist front and centre of the PROTAC revolution
February 2019
CRBN versus VHL: our new PROTAC paper on hijacking E3 ligases against each others is now published in Bioorg. Med. Chem.
Welcome to Jay who starts as new postdoc in the group
Our new paper describing an SPR kinetic assay to monitor PROTAC ternary complexes is now out in ACS Chemical Biology
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