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Ciulli Laboratory
School of Life Sciences, University of Dundee
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Alessio Ciulli
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Targeted Protein Degradation: PROTACs
Cullin RING E3 Ubiquitin Ligases
Chromatin-Reader Domains
Fragment-Based Ligand Discovery
Chemical Probes
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October 2020
On the front cover of Organic & Biomolecular Chemistry
Our chapter on structural biophysical principles of degraders ternary complexes is now published in the new RSC book 'Protein Degradation with New Chemical Modalities'
Almirall and the University of Dundee announce a multi-target research collaboration to develop novel Targeted Protein Degraders medicines
Welcome to the group to Andre, Anna, Charlotte and Tom!
August 2020
Welcome to Christa who joins the group as rotation student on the Wellcome Trust programme
Our new paper describing stereoselective syntheses of allele-selective BET inhibitors bumped-JQ1 is now out in the RSC journal Org. Biomol. Chem.
July 2020
Our review on probing epigenetic reader domains with chemical biology is now published in Current Opinion in Chemical Biology
Our collaborative work with Scott Lokey's Lab at UCSC on PROTAC structure-permeability relationships is now published in ACS Med Chem Lett
Claire and Alessio's News & Views story on Carolyn Bertozzi's group work on LYTACs is now published in Nature
HaloProtac meets AdProm! Our collaboration with the Sapkota and Ganley Labs is now published in Cell Chemical Biology
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