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Ciulli Laboratory

School of Life Sciences, University of Dundee

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    • Targeted Protein Degradation: PROTACs
    • Cullin RING E3 Ubiquitin Ligases
    • Chromatin-Reader Domains
    • Fragment-Based Ligand Discovery
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News

April 2021

  • Figure 1. Unbiased proteomics identify VHL protein level increase upon VHL inhibitor treatment
    New pre-print: VHL inhibitor binding increases intracellular level of VHL

March 2021

  • Graphical abstract
    Will and Manfred's review on the present and future of PROTACs for cancer therapy is now out in Current Opinion in Pharmacology
  • Professor Alessio Ciulli (Left) and Professor Sir Mike Ferguson (Right)
    £38 million investment in University spinout Amphista therapeutics
  • Selma
    Welcome to Selma, who joins the group as cell biologist postdoctoral scientist starting a new AC-Almirall Team
  • Claudia and Angus
    Congratulations to Angus and Claudia for being awarded Marie Sklodowka-Curie Individual Fellowships!

January 2021

  • Claudia & Xingui
    Welcome to Claudia and Xingui who join the group as postdocs

November 2020

  • Graphical abstract
    Our review on building and hijacking ubiquitination machineries by PROTACs and glues is now out in Current Opinion in Structural Biology
  • Sarah and Kevin
    Welcome to Kevin and Sarah who join the group as postdoc and rotation PhD student, respectively
  • SLAS Discovery journal cover
    Our review covering E3 ligase ligands for PROTACs is now published in SLAS Discovery

October 2020

  • ToC graphics
    Our review on synthetic medicinal chemistry of phosphotyrosine analogues and phosphomimetics is now published in RSC Medicinal Chemistry

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Prof Alessio Ciulli
Professor of Chemical and Structural Biology
School of Life Sciences, University of Dundee
Division of Biological Chemistry & Drug Discovery
1 James Lindsay Place
Dundee
DD1 5JJ
United Kingdom

E-mail: a.ciulli@dundee.ac.uk
Tel: +44 (0)1382 386230
Fax: +44 (0)1382 386373

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