University of Dundee

Postdoctoral Research Assistant

Unit: 
Medical Research Council Protein Phosphorylation and Ubiquitylation Unit
Job Reference: 
SLSC1074
Closing Date: 
Sunday, May 29, 2022
Salary: 
£33,309 - £40,927
The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 40 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.
 
We are recruiting for an exceptional individual to join us as a Postdoctoral Research Assistant within the laboratory of Professor Satpal Virdee, MRC Protein Phosphorylation and Ubiquitylation Unit (PPU).
 
Studies on the recently discovered neuronal E3 ligase MYCBP2

Applications are invited for a postdoctoral scientist in the lab of Prof. Satpal Virdee. This exciting project will involve research on the E3 ligase MYCBP2 recently discovered by the lab (Pao et al. Nature 2018; Mabbitt et al. Nat Chem. Biol. 2020). MYCBP2 uses an unprecedented mechanism that links the small protein modifier ubiquitin to hydroxy groups within substrates. MYCBP2 has critical roles in neuronal development and post-developmental programmed axon degeneration and is a compelling therapeutic target. This project will delineate the paradigm changing features of this central yet highly divergent component of the ubiquitin system at a molecular level. The post would suit those with research experience in the molecular sciences who are enthusiastic about applying multidisciplinary techniques to a cutting-edge area of research.

Who we’re looking for:

Motivated candidates should ideally have recently carried out a PhD working in biochemistry, structural biology or cell biology. The position will be a fantastic opportunity for candidates to broaden their skill set by working in an internationally competitive lab using state-of-the-art multidisciplinary technologies. The successful applicants will join an international team in an exciting and interactive environment, equipped to the very highest standards, and with generous consumable support. 



Candidate requirements:

  • PhD in a related discipline
  • Capable of working in a team, but able to plan and work independently.
  • Excellent communication skills and knowledge of the English language.
The position is available immediately and open to both international and UK candidates. The appointment will be made on the University of Dundee Grade 7 salary scale plus superannuation, with initial placement depending on achievements and experience.
 
Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. In this case the initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 25 – 28). 
 
Commitment to DORA

The School of Life Sciences has been fully committed to the principals of the San Francisco Declaration on Research Assessment (DORA) since 2013. In assessing applicants, we consider the scientific quality of their published research papers, but do not take into account where the papers were published and do not consider journal-based metrics, such as Journal Impact Factors.

 
Additional Information

We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.



The University of Dundee is a signatory of the Researcher Development Concordat and is committed to enhancing the research environment and culture. Engagement and support of activities which assist the researcher development agenda at the University is therefore essential.



MRC Protein Phosphorylation and Ubiquitylation Unit (PPU):

The MRC-PPU is one of the world’s most renowned centres for research on protein phosphorylation and ubiquitylation (http://www.ppu.mrc.ac.uk) and has an exciting and collaborative research environment, equipped to the highest international standards. The major aims of the MRC-PPU are to advance understanding of the role of protein phosphorylation and ubiquitylation in cell regulation and human disease; to facilitate the development of drugs to treat diseases caused by abnormalities in phosphorylation; and to generate reagents and improve technologies. Another key remit of the MRC-PPU is to train the next generation of scientists who will advance our understanding in this crucial area of medical research. The MRC-PPU is located in a beautiful setting overlooking the estuary of the River Tay and embedded within the School of Life Sciences at the University of Dundee.



For further information about this position please contact Satpal Virdee at s.s.virdee@dundee.ac.uk. To find out more about MRC PPU please visit https://www.ppu.mrc.ac.uk/.



As an internationally diverse institution, we welcome job applicants from all countries and nationalities.  The School of Life Sciences is proud to employ staff from over 40 different nations.



The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.



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