University of Dundee

Scientific Support Officer in Cryo-Electron Microscopy

Unit: 
Centre for Gene Regulation and Expression
Job Reference: 
SLSC0925
Closing Date: 
Saturday, October 2, 2021
Salary: 
Grade 7 (£32,817 - £40,322)

Summary of Job Purpose and Principal Duties

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 40 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

We are recruiting for an exceptional individual to join us as a Scientific Support Officer in Cryo-Electron Microscopy.

This is a new post within our Cryo-Electron Microscopy facility. The appointee will maintain and run the facility on a day to day basis, including managing bookings, training users, assisting with sample preparation and ensuring the safe operation of the microscope.

The Cryo-TEM is used in a multidisciplinary research environment, attending users from Biology, Chemistry and Physics working in a variety of projects, including solving protein structures; protein and polymer self-assembly; cellular and tissue.

The facility, which is open to both internal and external users and is also a feeder facility for access to the high-end Scottish cryo-TEM facility based in Glasgow, currently comprises 200KeV JEOL 2200FS CryoTEM electron microscope with FEG electron source and fitted with Gatan ultrascan 4Kx4K CCD camera. The microscope is set for single particle analysis, (cryo)-electron tomography and selected area diffraction method (MicroED). Digital micrograph and SerialEM are installed to drive the microscope and collect dataset.

The School of Life Sciences has recently secured >£1M of funding to greatly enhance our Cryo-EM capabilities through the purchase of a new system (Thermo Glacios microscope equipped with falcon 3EC detector, or similar), the successful candidate will have an excellent opportunity to be involved in the facility upgrade and management of equipment procurement, installation and commissioning.

Your priorities will include:

  • Ensuring the day-to-day running of the facility, including keeping the microscope aligned, troubleshooting where possible, maintaining contact with manufacturer and service engineers regarding microscope maintenance and troubleshooting
  • Train, assist and manage the multidisciplinary user base of the facility, ensuring that the users can obtain optimal results in a time-efficient manner. Assist with sample preparation and sample screening with aim of enabling users to operate independently.
  • Overseeing the installation of a new Cryo-EM, including commissioning and testing.
  • Attending meetings/workshops and discuss projects with the academic and industrial user base
  • Interface and cooperate with the newly-established SCMI in Glasgow as part of a Scotland-wide cryo-EM consortium to facilitate access to this 300 keV EM facility as well as the eBIC facility in Harwell.

Summary of Skills, Experience and Qualifications

  • Candidates should have a PhD (or soon to be awarded a PhD) in Biology, Chemistry, Physics, Material Sciences or related fields
  • Candidates should have hands-on experience of cryo-EM and conventional EM, including a detailed understanding of routinely used sample preparation techniques for both, as well as experience of data collection using single particle analysis and/or tomography.
  • Candidates should have strong interpersonal, communication, organisational, time management and presentation skills.
  • Candidates should have the ability to undertake day-to-day work, including running equipment as well as multi-tasking across several research projects.

This post is available for five years in the first instance, on a full-time basis.

Appointment on the University's Grade 7 salary scale is dependent upon you having been awarded a PhD.   An appointment may be considered if you are shortly expected to be awarded a PhD. In this case the initial appointment would be made on the University's Training Grade 7 salary scale.

Additional Information

We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.

For further information and informal enquiries please contact Tom Owen-Hughes (t.a.owenhughes@dundee.ac.uk) or Hannah Stanley (h.stanley@dundee.ac.uk). To find out more about our Cryo-EM Facility please visit https://www.lifesci.dundee.ac.uk/dundee-cryo-electron-microscopy-facility

As an internationally diverse institution, we welcome job applicants from all countries and nationalities. The School of Life Sciences is proud to employ staff from over 40 different nations.

The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.

The Closing Date is 2nd October 2021

For further information or to apply for this position please click here