University of Dundee

Postdoctoral Research Assistant

Centre for Gene Regulation and Expression
Job Reference: 
Closing Date: 
Thursday, July 16, 2020
Grade 7 (£32,817 - £40,322)

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

We are recruiting for an exceptional individual to join us as a Postdoctoral Research Assistant within the multidisciplinary lab of Daan van Aalten to work on developing vertebrate models of this disorder using CRISPR/Cas9.

This position is funded by a prestigious 5-year Investigator Award from the Wellcome Trust. The group has recently discovered a new neurodevelopmental syndrome leading to intellectual disability in young children, linked to mutations in the O-GlcNAc transferase (PNAS 2019, EJHG 2020). We work together with clinicians to understand genotype-phenotype links and are pursuing underpinning biological mechanisms.

The van Aalten lab is based in the Centre for Gene Regulation and Expression and is an exciting and collaborative research environment, equipped to the highest international standards. The School of Life Sciences is in a beautiful location overlooking the estuary of the River Tay and embedded within the School of Life Sciences at the University of Dundee. This is one of the premier Life Sciences research centres in the world and was recently assessed as the top UK University for Life Sciences research in the 2014 Research Excellence Framework (REF).

Candidate Requirements


  • PhD in field of vertebrate model biology
  • In possession of or about to obtain a personal license
  • Familiarity with basic laboratory techniques such as DNA and RNA extraction, PCR, gel electrophoresis and Western blots.
  • Good manual dexterity and ability to perform delicate collection actions.
  • Capable of working in a team, but able to plan and work independently.
  • Excellent communication skills to coordinate with lab members.
  • Ability to follow specific protocols and verbal direction.
  • Mathematical ability as needed to accurately execute and modify recipes according to volume needed.
  • Good organisational and time management skills.
  • Willingness to assist and communicate with other team members of the laboratory.
  • Demonstrable interest in supervising PhD students.


  • A background neurobiology/developmental biology
  • Experience with mouse genetics

Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 25 - 28 £29,176 - £31,866).

Apply Here

For further information about this position please contact Professor Daan van Aalten at

To find out more about the van Aalten lab please visit our website:

The University's statement on the use of animals in research can be found here:

We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.

The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.