University of Dundee

Postdoctoral Research Assistant (in bacterial virulence factor biosynthesis)

Unit: 
Molecular Microbiology
Job Reference: 
SLSC0753
Closing Date: 
Sunday, August 16, 2020
Salary: 
Grade 7 Training (£29,176 - £31,866)

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

We are recruiting for an exceptional individual to join us as a Postdoctoral research assistant within the Helge Dorfmueller laboratory, to study and target bacterial carbohydrate biosynthesis pathways. The focus of the work is on studying the enzymes responsible for the synthesis of the bacterial streptococcal surface carbohydrate and its role in the virulence (see van Sorge et al., 2014, van der Beek et al., 2015 and 2018, Zorzoli, Meyer et al., 2019). This position, which is funded by the Wellcome Trust and Royal Society, and is initially available from September 2020 for a period of 12 months.

The successful candidate will have an outstanding academic record, a PhD in molecular glycobiology or related discipline and at least one first author publication in an internationally recognised, peer-reviewed scientific journal. Experience in molecular biology and protein purification is expected.

A research background in the areas of carbohydrate biosynthesis and analysis by mass-spectrometry, assay development is highly desirable. Experience in structural biology studies would be advantageous. The successful candidates will be encouraged to demonstrate independence and innovative thinking whilst being an integral part of the lab team and will have the opportunity to learn new techniques and approaches within our lab and those of collaborators. Candidates must have the ability to work as part of a team, but be able to plan and work independently, and must have excellent communication skills and proficiency in English.

The Dorfmueller lab is based in the Division of Molecular Microbiology, within the School of Life Sciences at the University of Dundee. The Division of Molecular Microbiology is a dynamic and friendly work environment and the School of Life Sciences is recognised as a top UK and international centre for research in the Life Sciences.

Informal enquiries may be made to h.c.z.dorfmueller@dundee.ac.uk. Applications sent to Dr Dorfmueller directly will not be considered. Only applications via the University of Dundee website are considered.

Candidate requirements:

  • PhD in field of biochemistry / molecular glycobiology or related discipline
  • Experience in molecular biology (E coli) and bacterial expression systems (E. coli)
  • Strong background in protein biochemistry including purification
  • Experience in enzyme assay development (e.g. HPLC, Mass-spectrometry,TLC, radiolabelling)
  • Ability to work in a team, and being self-motivated, pro-active and able to plan and work independently

Desirable:

  • Background in Gram-positive bacteria
  • Experience in structural biology
  • Experience in Glyco-engineering

Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale.

Apply Here

We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Conveniently located on the banks of River Tay, our main city-centre campus is at the heart of Dundee - an up-and-coming, friendly, compact and affordable city with a rich heritage in design and technology. Just a short walk from the V&A Museum of Design Dundee, we’re close to both the train and bus stations. We also have campuses at Ninewells Hospital and in Kirkcaldy which are easily accessible via local transport links.

For further information about this position please contact Helge Dorfmueller at hczdorfmueller@dundee.ac.uk. To find out more about the Dorfmueller Group, Division of Molecular Microbiology and School of Life Sciences please visit https://www.lifesci.dundee.ac.uk/people/helge-dorfmueller and https://www.lifesci.dundee.ac.uk/research/mmb,

The diversity of our staff and students helps to make the University of Dundee one of the top universities in the UK. Family friendly policies, staff support networks for BME and LGBT staff, membership of Athena Swan and Stonewall, as well a full range of disability services, create an enjoyable and inclusive place to work.