University of Dundee

Molecular/ Cellular Biologist

Unit: 
Biological Chemistry and Drug Discovery
Job Reference: 
SLSC0496
Closing Date: 
Monday, December 3, 2018
Salary: 
Grade 7 (£32,236 - £39,609)
The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.
 
Main duties/responsibilities
 
We are seeking to appoint a highly motivated researcher with appropriate skills in molecular and cell biology to join our Mechanism of Action (MOA) group to work on malaria. The MOA group is embedded within the newly formed Wellcome Centre for Anti-Infectives Research (WCAIR) (http://www.lifesci.dundee.ac.uk/research/wcair) at the University of Dundee. The vision for the WCAIR is to tackle the urgent unmet medical need and lack of drug discovery research for Neglected Tropical Diseases (NTDs). WCAIR aims to integrate research in fundamental biology and translational research, exemplified by the Drug Discovery Unit (www.drugdiscovery.dundee.ac.uk), to deliver high-quality pre-clinical drug candidates for NTDs. A key focus of research in WCAIR is kinetoplastid and apicomplexan parasites, organisms which cause a variety of severe diseases in humans and animals.
 

The MOA group investigates mechanisms of drug action in kinetoplastid parasites. The group works alongside existing research groups within WCAIR, developing and employing cutting edge molecular biology, cell biology and biochemical tools to define drug mechanisms in Trypanosoma brucei, Leishmania spp. and T. cruzi. Our intention is to expand our current repertoire of tools to facilitate MOA studies in Plasmodium spp. The successful candidate will lead the development of our molecular biology, cell biology and biochemical tools in this apicomplexan parasite. This is a fantastic opportunity to join a group whose most recent publications have featured in Nature and PNAS. This position is for one year in the first instance.

Personal specification:

• A Ph.D. in a relevant subject, such as molecular biology or biochemistry.

• Extensive experience in molecular biology is essential.

• Extensive experience in cell culture is essential.

• Previous experience in the culture and genetic manipulation of Plasmodium spp would be highly advantageous.

• Experience of culturing category 2 pathogens (preferred).

• Computer and data processing/management skills are desirable

• Ability to work independently and/or as part of a team

• Good communication skills – written/verbal

• Track record of publication in peer-reviewed journals

Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment will be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 28, £31,302).

For more information please contact: Susan Wyllie (s.wyllie@dundee.ac.uk) and visit the MOA website (http://www.lifesci.dundee.ac.uk/other/kptools).

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The diversity of our staff and students helps to make the University of Dundee one of the top universities in the UK. Family friendly policies, staff support networks for BME and LGBT staff, membership of Athena SWAN and Stonewall, as well a full range of disability services, create an enjoyable and inclusive place to work.