University of Dundee

Postdoctoral Research Assistant (PS)

Unit: 
Plant Sciences
Job Reference: 
SLSC0358
Closing Date: 
Friday, March 2, 2018
Salary: 
Grade 7 (£31,604 - £38,833)
Closing Date 02 March 2018
 
Project: DogTag – a genetically encoded proximity labelling strategy to capture problematic protein-­protein interactions

Applications are invited for a postdoctoral position funded by the BBSRC. We are looking for an enthusiastic and motivated post-doctoral scientist to develop a new strategy to map protein-protein interactions.

Capturing protein-protein interactions is key to understanding biological processes. There are many existing strategies to investigate protein-protein interactions but none allow for naïve, non-invasive in-vivo examination of weak or transient proteins interactions under physiologically relevant conditions. We have identified a novel genetically encoded proximity labelling approach able to overcome these limitations.

This projects ultimate aim is to develop the method and enable differential discovery screens of protein-protein interactions in whole organisms under biologically relevant stimuli.

Applicants should have, or be about to obtain, a PhD, and have a solid background in molecular biology and biochemistry. Experience in working with plants and yeast, methods development, membrane proteins, protein-protein interaction screening and proteomics data analysis would be advantageous.

The position is in the laboratory of Dr. Piers Hemsley at the University of Dundee (School of Life Sciences; Division of Plant Sciences - http://www.lifesci.dundee.ac.uk/ps) based at the James Hutton Institute. Dundee (http://www.lifesci.dundee.ac.uk/) is currently ranked as the #1 University in the UK for life science research by the UK government research assessment (REF 2014) with world leading expertise in cell signalling and proteomics and outstanding laboratory and technology facilities for fundamental research and translation. With more than 900 staff from over 60 countries worldwide, the School of Life Sciences enjoys an international reputation as one of the most vibrant and productive research centres in Europe and is frequently voted “the best place to work in Europe” by readers of The Scientist magazine. The James Hutton Institute is the largest plant breeding and research institute in Scotland with particular expertise in translational plant science.

This post is available for up to 24 months, start date April-June 2018.
 

Informal enquiries are welcome: Dr Piers Hemsley, e-mail: p.a.hemsley@dundee.ac.uk
 
Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment will be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 28, £30,688).
 
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