The University of Dundee is joining a global effort – with the help of funding from the Chan Zuckerberg Initiative – to support development of the Human Cell Atlas, a global effort to map every type of cell in the healthy human body as a resource for studies of health and disease.
School of Research
In this seminar, Dr Uringa will discuss Taconic’s capabilities in mouse model generation. The focus will be on the use of CRISPR technology. As an example of CRISPR/Cas9 versatility, he will describe its combination with gene targeting to introduce complex modifications in the mouse genome.
An exciting new long-term collaboration has been launched between Dundee Rep Theatre and the School's Wellcome Centre for Anti-Infectives Research where together they will develop a series of innovative and diverse engagement and performance opportunities for local communities.
Dr Virdee and colleagues in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) have discovered a novel class of E3 ligase. The E3 ligase, MYCBP2, operates in a unique way, selectively transferring ubiquitin to non-lysine amino acids with selectivity for threonine. The ubiquitin is linked to the threonine amino acid via a chemically distinct ester linkage thereby uncovering an unanticipated area of cellular biology. The findings are published in Nature.
Professor Sir Ian Wilmut – who led the team that created Dolly the sheep – has backed an initiative to tackle Parkinson’s disease, after being diagnosed with the condition.
Biological structures are different from manmade structures in that they can grow and adapt while maintaining structural integrity. For example, bones remodel depending on the structural demands due to the exercise and weight of the animal. Plants strengthen their stems in response to physical distress, such as the increase in size and weight or being bent. A representative example is reaction wood formation, in which plants locally generate extra wood, a major load-bearing tissue, where extra structural support is needed.
She is one of the world’s most famous ships and is synonymous with British scientific endeavour, and more than a century after her historic expedition to Antarctica, RRS Discovery is still revealing her secrets.