Professor Irwin McLean has been elected as a Member of the Academia Europaea. Academia Europaea is a highly prestigious organisation whose members across Europe are scientists and scholars who collectively aim to promote learning, education and research. “I am delighted, surprised and honoured to have been elected to Academia Europaea.
Staphylococcus aureus is a major global pathogen. In addition to a wide spectrum of human diseases, S. aureus causes economically important infections of cows, sheep, poultry, and rabbits. We have been investigating the evolutionary history of S. aureus clones associated with different host species, the molecular basis for host-adaptation, and the emergence of antibiotic resistance. Using a time-scaled phylogenetic approach, we have identified ancient and recent host-switching events leading to the emergence of endemic and epidemic clones in humans and livestock.
Bacteriophages play major roles in the biology of their bacterial hosts, driving bacterial pathogenicity, genome evolution and population dynamics. Additionally phages are being explored as alternatives to antibiotics for problematic infections, due to their ability to specifically lyse bacterial cells. Clostridium difficile infection (CDI) is a major healthcare problem associated with exposure to antibiotics. Part of the difficulty in combating CDI is the constant emergence of novel genotypes (ribotypes) in clinics. Outside the hospital environment, C.
An enzyme crucial to the process of DNA repair in our cells has been mapped in atomic detail by researchers at the University of Dundee, the UK’s top-rated University for Biological Sciences.
DNA repair plays a key role in human diseases such as cancer. Researchers say that revealing the 3D molecular structure of a key enzyme involved in this process could be an important step towards developing future drugs.
Researchers including Dr Sara Brown and Professor Irwin McLean from the University of Dundee have discovered 10 new genetic variants that help determine which people will develop eczema, highlighting potential new targets for therapeutic research.
Professor Irwin McLean of the University of Dundee has been awarded the prestigious Buchanan Medal of the Royal Society.
The Buchanan Medal is awarded by the Royal Society, the world’s oldest scientific academy in continuous existence, for distinguished contributions to the medical sciences.
We are seeking an experienced scientist to work as Scientific Officer on a project aimed at the development of small molecule therapeutics for human skin disease in collaboration with the Drug Discovery Unit. Applicants should have a degree in biology, chemistry, or pharmacology. You must have substantial experience in genetics, molecular biology, microbiology, tissue culture, quantitative PCR, protein biochemistry, RNA biochemistry, immunoassays, high-throughput screening and have some experience in statistical analysis.
We are seeking a research technician for a project aimed at the development of therapeutics for human skin disease. Applicants should have good A-level or equivalent Higher qualifications, or a degree in a biological subject. Previous laboratory experience in small animal handling, nucleic acid extraction, quality control and basic molecular biology techniques would be a distinct advantage.