Three PhD students in the School have been selected to join Europe’s finest University students in creative and intellectual collaboration at Roche Continents 2018.
Medical Research Council Protein Phosphorylation and Ubiquitylation Unit
We are looking for an enthusiastic research technician to join a team involved in running and optimizing PCR for genotyping from small tissue samples and also assisting with various in vivo studies. The responsibilities also include recording routine study data using electronic system and coordinating in vivo experiments. As you are required to be involved in various in vivo studies, experience in with in vivo models is essential. Possession or willingness to possess a Home Office personal license is essential.
Joint MRC Protein Phosphorylation and Ubiquitylation, Cell Signalling and Immunology and Tayside Immunology Group Seminar
Professor Muller is a renowned expert in the area of molecular nutrition related to lipid homeostasis, nutrigenomics and nutritional systems biology and his work is focussed on the molecular mechanisms underlying genome-wide effects of foods (specific bioactive components or nutrients) on immuno-metabolic health and plasticity.
New research by Greg Findlay’s group in the MRC-PPU has made progress in understanding the fundamentals of intellectual disability, a developmental disorder thought to affect 1-2% of the world’s population. The paper by Francisco Bustos, a post-doctoral investigator, and Anna Segarra-Fas, a PhD student in Greg’s lab, shows that genetic mutations found in intellectual disability patients impair the catalytic activity of an E3 ubiquitin ligase called RNF12.
The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded MRC PPU Director Dario Alessi the 2018 MJFF Langston Award for “service and dedication to our shared goals of advancing Parkinson's understanding and therapeutic development”. For further information see here.
Mitochondrial and Membrane Trafficking mechanisms in Parkinson’s disease in the laboratory of Dr Miratul Muqit, at the University of Dundee. Dr Muqit is a Physician-Scientist whose lab funding includes the Wellcome Trust and EMBO.
In this seminar, Dr Uringa will discuss Taconic’s capabilities in mouse model generation. The focus will be on the use of CRISPR technology. As an example of CRISPR/Cas9 versatility, he will describe its combination with gene targeting to introduce complex modifications in the mouse genome.