University of Dundee

Medical Research Council Protein Phosphorylation and Ubiquitylation Unit

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New MRC PPU and CVR Coronavirus Toolkit Website Launched

Researchers within the Reagents and Services division of the MRC PPU and the MRC-University of Glasgow Centre for Virus Research (CVR) have worked extremely hard since January in order to produce expression plasmids, proteins and sheep affinity purified polyclonal antibodies to all 28 proteins encoded for by SARS-CoV-2. In addition, they have generated equivalent reagents to 10 other proteins from related Coronaviruses.

MRC PPU contributes to UK consortium providing essential reagents for SARS-CoV-2 research

Launching today, Tuesday 12 May, the COVID-19 Protein Portal allows UK scientists to access protein reagents for critical research relating to SARS-CoV-2. Protein reagents are provided free of charge by a consortium of leading protein production laboratories, in an Open Science initiative led by Wellcome and UKRI.

Postdoctoral Research Assistant

The laboratory of Miratul Muqit at the MRC PPU, University of Dundee is looking to appoint two Postdoctoral Research Assistants to explore cell signalling, mitochondria, and autophagy mechanisms in Parkinson’s disease. The positions are funded by the Wellcome Trust and are available for 3 years in the first instance.

Postdoctoral Researcher

Summary of Job Purpose and Principal Duties

The Kulathu Lab at the MRC PPU, University of Dundee is looking to hire a Postdoctoral Researcher with strong expertise in biochemistry to address exciting questions about the mechanisms and function of the essential but poorly understood posttranslational modifier UFM1. The project is funded by a BBSRC grant awarded recently to the lab, and the position is available for 3 years.

Summary of Skills, Experience and Qualifications

Online research conference involving Dundee draws national attention in Kazakhstan

Despite the coronavirus lockdown, researchers from MRC PPU are continuing to attend online meetings, seminars and conferences to share ideas with researchers around the world. Last week, Nicola Darling, a postdoctoral researcher in Philip Cohen’s lab, moderated the Health and Sustainable Development session at the Third Central Asian Research Forum on Sustainable Development and Innovation that involved researchers based in or from Kazakhstan.

Postdoctoral Research Assistant

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

Project: Dissecting AMPK/AMPK-related kinase signalling through Affinity-directed PROtein Missile (AdPROM) system

Dundee researchers target protein to tackle COVID-19

University of Dundee researchers are studying a protein that aids the spread of COVID-19 in the hope of finding ways of blocking its function.

The team, from the University’s Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) are working in partnership with the Drug Discovery Unit (DDU) to study an enzyme found within the SARS-CoV-2 virus that causes COVID-19 infection.