University of Dundee

Cell Signalling and Immunology

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SLS Researchers at Dundee Science Festival and SLS ‘Open Doors Day’

Last month many researchers from the School took part in the annual Dundee Science Festival and School ‘Open Doors Day’. “It was fantastic to see representation from across the whole School in these recent public engagement events. It is a key skill for scientists at all levels to be able to not only communicate their research to people of all ages and educational backgrounds but to also interact and listen to these individuals as well,” said Professor Julian Blow, Dean of Life Sciences.

Jenny Woof made Professor

Jenny Woof has been promoted to Personal Chair (Professor) to add to her position as Associate Dean for Quality and Academic Standards in the School. "I am delighted to congratulate Jenny Woof on her Personal Chair. This is a fitting acknowledgment of the outstanding contributions she has made to the academic life of the School and her work as Associate Dean for Quality and Academic Standards" said Professor Julian Blow, Dean of School of Life Sciences.

Diabetes group `adopts’ University research projects

A Dundee-based diabetes support group is `adopting’ two research projects at the University of Dundee.

Dundee Diabetes Scotland Group has been running for over 50 years and works to support sufferers of Diabetes to help manage their condition. The group is now winding down but is bowing out with a generous gesture to researchers at the University, one of the UK’s leading centres for diabetes research.

Technician (Full or Part-Time)

A full or part-time post is available in Professor Doreen Cantrell's Research group in the Division of Cell Signalling and Immunology at the School of Life Sciences. The research objective of the laboratory is the characterization of signal transduction pathways in T lymphocytes using transgenic lines as model systems.

The successful candidate’s primary duty will be the analysis of the transgenic lines by routine PCR genotyping under close liaison with all members of the group. The candidate will also be required to help with the day-to-day running of the laboratory.

'Molecular commando' identified to tackle hypoxia pathway

Scientists at the University of Dundee have identified a `molecular commando’ which can be stealthily deployed to activate a hypoxic response, a process which can help to fight a range of conditions including stroke, angina, colitis and brain injuries.

A Dundee team led by Professor Alessio Ciulli have used pioneering techniques to develop a `small molecule’ chemical probe called VH298, which offers highly targeted access to the parts of the cell which regulate hypoxia, known as the hypoxic signalling pathway.

“Immune communication at inflammatory sites: not so silent signals!”

Dr Megan MacLeod graduated from the University of Glasgow in 2001 with a first class honours in Immunology and received her PhD from the University of Edinburgh in 2005. Her research took her to Denver, USA where she worked with Philippa Marrack and John Kappler. She is currently a research fellow at the Institute of Infection, Immunity and Inflammation at the University of Glasgow. Her research is focused on understanding the cellular and molecular differences that enable memory CD4 T cells to respond differently from their naïve counterparts.