University of Dundee

Cell Signalling and Immunology

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CSI

Discovery raises possibility of asthma treatment

A University of Dundee researcher has uncovered why parasitic worm infections seem to protect people from developing asthma, paving the way for potential future treatments for the disease.

Although it has been known for some time that parasites called roundworms, which live in the intestines of people and animals, can prevent the development of allergic immune responses, scientists have been unable to explain how this happens.

Scottish funding for Dundee Covid-19 research project

Scientists and clinicians based at the Schools of Life Sciences and Medicine at the University have been awarded funding from the Chief Scientist Office that will help identify those most vulnerable to severe symptoms of coronavirus.

The team led by Professor Doreen Cantrell, a Professor of Cellular Immunology and Professor James Chalmers, a leading respiratory disease physician at Ninewells, has been awarded £294,000 to help identify patients experiencing symptoms of Covid-19 whose condition could significantly worsen.

Neutrophil Protocol for Parkinson’s research into LRRK2 published

A protocol for utilizing human peripheral blood neutrophils for research into the Parkinson’s disease associated LRRK2 kinase has been published. The collaborative work led by Esther Sammler, Clinical Programme Leader in the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit in the School and Clinical Senior Lecturer & Honorary Consultant in the School of Medicine.

Awards recognition for outstanding microscopy images

Alan Prescott has been chosen to be the regional (Europe) EMEA winner of the Olympus Image of the Year Award 2019. This was for the submitted image with the title "The mouse’s whiskers: image from a frozen section of the head from the mito-QC mouse."

This win follows a very successful 12 months where Alan’s microscopy work has been recognised in five other national and international competitions.

New collaboration will harness latest technology to uncover role of proteins in neurodegenerative disease

A pioneering collaboration between the UK Dementia Research Institute (DRI) and the Medical Research Council’s Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) will use the very latest advances in technology to study rare cell populations and the role of proteins in diseases such as Alzheimer’s and Parkinson’s.

Scientists discover how rogue communications between cells lead to Leukaemia

New research has deciphered how rogue communications in blood stem cells can cause Leukaemia. The discovery, published in the journal Science, could pave the way for new, targeted medical treatments that block this process. Blood cancers like leukaemia occur when mutations in stem cells cause them to produce too many blood cells.

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