A short-term post-doc position is available in Professor Kate Storey's group from August 2020 to end of July 2021. There may also be a possibility of an extension pending new grant support. The position will involve developing our ongoing work with a human iPS cell derived neural differentiation assay to investigate cell biological mechanisms that regulate neurogenesis. This will involve generating and characterising reporter hiPS cell lines and their use in live cell imaging experiments to monitor cell behaviour and how this changes in stress conditions.
Cell and Developmental Biology
Researchers in the School have discovered a new neurodevelopmental disease caused by genetic mutations and helped explain why patients with these mutations suffer this condition.
Around 1% of the global population are affected by intellectual disability, a condition characterised by significant limitations in both intellectual function and in adaptive behaviour. It was known that a molecule called GlcNAc was found on proteins related to intellectual disability, but its exact role in this disease remained unclear.
Megan Bergkessel and Leeanne McGurk have been awarded funding from the Springboard scheme of the Academy of Medical Sciences, which is designed to help early career researchers establish their independent research programmes.
The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.
I did my PhD with Roberto Mayor at UCL, where my main project showed how a switch between E- and N- Cadherin drives the acquisition of contact inhibition of locomotion and leads to the redistribution of forces from intercellular junctions to cell-matrix adhesions in Xenopus and Zebrafish neural crest cells (Scarpa et al., Dev Cell 2015,