University of Dundee

2019

Deegan T, Baxter J, Ortiz Bazan M, Yeeles JTP, Labib K. 2019. Pif1-family helicases support fork convergence during DNA replication termination in eukaryotes. Molecular Cell. 74(2):231-244.e9. https://doi.org/10.1016/j.molcel.2019.01.040

Deng L, Wu RA, Sonneville R, Kochenova OV, Labib K, Pellman D, Walter JC. 2019. Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. Molecular Cell. 73(5):915-929.e6. https://doi.org/10.1016/j.molcel.2018.12.021

Kelsall IR, Kristariyanto YA, Knebel A, Wood NT, Kulathu Y, Alpi AF. 2019. Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling. Journal of Biological Chemistry. 294(8):2651-2664. https://doi.org/10.1074/jbc.RA118.005861

Livingston MJ, Wang J, Zhou J, Wu G, Ganley I, Hill JA, Yin X-M, Dong Z. 2019. Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys. Autophagy. https://doi.org/10.1080/15548627.2019.1615822

McWilliams TG, Ganley IG. 2019. Investigating Mitophagy and Mitochondrial Morphology In Vivo Using mito-QC: A Comprehensive Guide. Ktistakis N, Florey O, editors. In Autophagy: Methods and Protocols. New York: Humana Press. pp. 621-642. (Methods in Molecular Biology). https://doi.org/10.1007/978-1-4939-8873-0_41

McWilliams TG, Prescott A, Villarejo-Zori B, Ball G, Boya P, Ganley I. 2019. A comparative map of macroautophagy and mitophagy in the vertebrate eye. Autophagy. https://doi.org/10.1080/15548627.2019.1580509

Miller S, Muqit MMK. 2019. Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinson's disease. Neuroscience Letters. 705:7-13. https://doi.org/10.1016/j.neulet.2019.04.029

Nisr R, Shah D, Ganley I, Hundal H. 2019. Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-019-03148-8

Roth S, Fulcher L, Sapkota G. 2019. Advances in targeted degradation of endogenous proteins. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-019-03112-6

Tovell H, Testa A, Maniaci C, Zhou H, Prescott A, Macartney T, Ciulli A, Alessi D. 2019. Rapid and reversible knockdown of endogenously tagged endosomal proteins via an optimized HaloPROTAC degrader. ACS Chemical Biology. 14(5):882-892. https://doi.org/10.1021/acschembio.8b01016

Zhang P, Fan Y, Ru H, Wang L, Magupalli VG, Taylor SS, Alessi DR, Wu H. 2019. Crystal structure of the WD40 domain dimer of LRRK2. Proceedings of the National Academy of Sciences of the United States of America. 116(5):1579-1584. https://doi.org/10.1073/pnas.1817889116