Principal Investigators
Dario Alessi Professor of Signal Transduction and Co-Director of MRC-PPU and SCILLS
Regulation and physiological roles of protein kinases 		MRCPPU
Gabriela Alexandru Programme Leader in Protein Ubiquitylation
The role of p97 and its UBX-domain cofactors in health and disease 		SCILLS
Arno Alpi Programme Leader in Protein Ubiquitylation
The role of ubiquitylation in responses to DNA damage 		SCILLS
Simon Arthur Programme Leader in Protein Phosphorylation
Control of transcription in the immune system and CNS 		MRCPPU
Geoff Barton Professor of Bioinformatics
Protein and nucleic acid sequence analysis and functional predictions 		BCDD
Elizabeth Bayne Principal Investigator
Non-coding RNAs and chromatin modification 		GRE
Paul Birch Professor of Plant Pathology
Plant pathogen interactions 		PS
Mikael Bjorklund Wellcome Trust Career Development Fellow and Lecturer
Regulation of cell growth in multicellular organisms. 		CDB
Sue Black Professor of Anatomy and Forensic Anthropology
Director of CAHID, Human Identification research, expert forensic practicioner 		CAHID
Julian Blow Professor of Chromosome Maintenance and Deputy-Head of the Wellcome Trust Centre for Gene Regulation and Expression
How DNA replication is organised and controlled to ensure precise chromosome duplication 		GRE
Ruth Brenk Lecturer in Computational Chemistry
Developing and applying computational methods to predict the interactions of small molecules with macromolecules. 		BCDD
John Brown Chair of Molecular Plant Sciences and Head of the Division of Plant Sciences PS
Paul Campbell Associate Principal Investigator
The application of Physics to Biology 		MM
Doreen Cantrell Professor of Cellular Immunology, Wellcome Trust Principal Research Fellow and Vice Principal and Head of College
T-lymphocyte signal transduction 		CSI
Jonathan Chubb Wellcome Trust Senior Research Fellow
Control of noise in gene expression 		CDB
Geoffrey Codd Emeritus Professor of Microbiology
Cyanotoxins and microbial metabolites 		MMB
Tricia Cohen Professor of Molecular Biology
Protein phosphotases in cellular regulation 		MRCPPU
Philip Cohen Director of the MRC Protein Phosphorylation Unit and Director of the Scottish Institute for Cell Signalling
The interplay between protein phosphorylation and protein ubiquitylation in regulating innate immunity. 		MRCPPU
Sarah Coulthurst Royal Society of Edinburgh Research Fellow
Bacterial pathogens and protein secretion systems 		MMB
Victoria Cowling MRC Career Development Fellow
The function of c-myc and RNA cap methylation 		CSI
Paul Crocker Professor of Basic Biomedical Science, Wellcome Trust Senior Fellow and Associate Dean of Postgraduate Matters
Carbohydrate recognition in the immune system 		CSI
Kim Dale Royal Society University Research Fellow
Establishing the vertebrate embryonic body plan 		CDB
Alan Fairlamb Professor of Biochemistry, Wellcome Principal Research Fellow and Head of the Division of Biological Chemistry and Drug Discovery BCDD
Mike Ferguson Professor of Molecular Parasitology and Dean of Research
Molecular parasitology, glycobiology and drug discovery 		BCDD
Andy Flavell Professor of Plant Genomics
Structure, evolution and biodiversity of crop plant genomes 		PS
Geoff Gadd Boyd Baxter Professor of Biology
Geomicrobiology 		MMB
Ian Ganley Programme Leader
Molecular regulation of autophagy in health and disease 		MRCPPU
Anton Gartner Wellcome Trust Senior Research Fellow and Reader
C. elegans genetics as a model to study basic biological problems 		GRE
Ian Gilbert Professor of Medicinal Chemistry and Deputy-Head of the Division of Biological Chemistry and Drug Discovery
Design and synthesis of potential therapeutic agents 		BCDD
David Gray Head of Biology
Molecular Pharmacology and Compound Screening 		BCDD
Eric Griffis Wellcome Trust Research Career Development Fellow
Myosin II redistributes rapidly as cells progress from metaphase to anaphase 		GRE
Claire Halpin Professor of Plant Biology and Biotechnology and Deputy Head of the Division of Plant Sciences
Manipulation of plant metabolism using reverse genetics 		PS
Grahame Hardie Professor of Cellular Signalling
The LKB1-AMPK signalling cascade 		CSI
Ron Hay Professor of Molecular Biology
Role of ubiquitin and ubiquitin-like proteins in transcriptional regulation 		SCILLS
Andrew Hopkins Professor of Medicinal Informatics and SULSA Research Professor of Translational Biology
Chemoinformatics, chemogenomics and drug discovery 		BCDD
Edgar Huitema Royal Society of Edinburgh Research Fellow
Mechanisms of virulence acquisition during Phytophthora-host associations 		PS
Hari Hundal Professor of Molecular Physiology and Deputy Head of the Division of Cell Signalling and Immunology
Hormonal, nutrient and stress-mediated regulation of glucose and amino acid transport 		CSI
Bill Hunter Professor of Structural Biology
Protein structure and function; fundamental chemical biology and early stage antimicrobial drug discovery 		BCDD
Gyorgy Hutvagner Wellcome Trust Career Development Fellow
Gene regulation by micro-RNAs 		GRE
Arnaud Javelle Royal Society of Edinburgh Research Fellow
Transport of ions across cellular membranes and in signalling processes relating to ion availability. 		MMB
Thimo Kurz Programme Leader in Protein Ubiquitylation
Function and regulation of ubiquitin and ubiquitin-like conjugation systems 		SCILLS
Angus Lamond Professor of Biochemistry and Director of the Wellcome Trust Centre for Gene Regulation and Expression
Nuclear structure and gene expression 		GRE
Nick Leslie RCUK Academic Fellow
Lipid based signal transduction mechanisms and their roles in cancer 		CSI
David Lilley Professor of Molecular Biology and Director of the Cancer Research UK Nucleic Acid Structure Research Group
Nucleic acid structure 		NASRG
Carol MacKintosh Professor of Molecular Signalling and group leader in MRC PPU
14-3-3s in cellular responses 		MRCPPU
Miguel Maroto Lecturer
Molecular mechanism of cyclic Notch signalling 		CDB
Irwin McLean Professor of Human Genetics and Head of the Division of Molecular Medicine
Dermatology and Genetic Medicine - treating genetic disease 		MM
Arno Muller MRC Non-Clinical Senior Research Fellow and Reader
Cell signaling networks in polarised tissue establishment and remodeling 		CDB
Inke Nathke Professor Epithelial Biology and Cancer
From molecules to tissue architecture 		CDB
Timothy Newman Professor of Biophysics & SULSA Research Professor of Systems Biology
Theoretical and computational analysis of fluctuations in biological systems. 		CDB
Andrei Nikolaev Reader in Organic Chemistry
The chemical synthesis of complex phosphosaccharides 		BCDD
David Norman Senior Lecturer in Structural Biology
Magnetic Resonance, FRET, EPR, Spin-labeling and PELDOR 		NASRG
Tom Owen-Hughes Professor of Chromatin Structure and Function, Wellcome Trust Senior Research Fellow
Chromatin structure and gene regulation 		GRE
Tracy Palmer Professor of Molecular Microbiology and Head of the Division of Molecular Microbiology
Protein transport across bacterial membranes 		MMB
Patrick Pedrioli Programme Leader in Protein Ubiquitylation
Mass-spectometric methods to study ubiquitylation 		SCILLS
Alan Prescott Senior Lecturer in Cell Biology
The role of the cytoskeleton in cell specific differentiation 		CSI
Kevin Read Head of DMPK for the Drug Discovery Unit
Distribution, metabolism and pharmacokinetics of drugs 		BCDD
Sonia Rocha CR-UK Senior Research Fellow and Lecturer
Investigating the mechanisms controlling gene expression in hypoxia 		GRE
John Rouse Programme Leader in Protein Phosphorylation
Responses to DNA damage 		MRCPPU
Kei Sakamoto Programme Leader in Protein Phosphorylation
Intracellular signalling and exercise 		MRCPPU
Gopal Sapkota Programme Leader in Protein Phosphorylation
TGFβ signalling in disease 		MRCPPU
Frank Sargent Professor of Bacterial Physiology
Assembly and targeting of complex bacterial enzymes 		MMB
Pauline Schaap Professor of Developmental Signalling
Experimental and evolutionary reconstruction of developmental signalling pathways 		CDB
Gordon Simpson Reader
RNA and Development 		PS
Roger Soames Cox Professor of Anatomy
Professor in functional and applied anatomy, CAHID senior management 		CAHID
Nicola Stanley-Wall Lecturer in Molecular Microbiology
Understanding the molecular mechanism of biofilm formation 		MMB
Mike Stark Professor of Yeast Molecular Biology
Regulation of Yeast Cell Growth and Division 		GRE
Kate Storey Professor of Neural Development and Head of the Division of Cell and Developmental Biology
Neural differentiation in embryos and embryonic stem cells 		CDB
Jason Swedlow Professor of Quantitative Cell Biology
Mitotic chromosome dynamics 		GRE
Tomo Tanaka Professor of Cell and Molecular Biology
Chromosome duplication and segregation in the cell division cycle 		GRE
Pete Taylor Senior Lecturer in Molecular Physiology CSI
Matthias Trost Programme Leader and Head of Proteomics
Proteomics and signalling events regulating phagosome biogenesis 		MRCPPU
Daan van Aalten Professor of Biological Chemistry
Structural mechanisms and inhibition of protein-carbohydrate interactions in cell signalling, immunity and host-pathogen interactions 		MMB
Satpal Virdee Programme Leader SCILLS
Colin Watts Professor of Immunobiology and Head of the Division of Cell Signalling and Immunology
Antigen processing and the immunobiology of dendritic cells 		CSI
Kees Weijer Professor of Developmental Physiology and Head of Systems Biology
Cell-cell signalling and chemotactic cell movement during development 		CDB
Caroline Wilkinson Professor of Craniofacial Identification
Facial anthropology and forensic facial reconstruction, CAHID senior management 		CAHID
Jeff Williams Wellcome Trust Principal Research Fellow
Signal transduction pathways that regulate Dictyostelium gene expression 		CDB
Paul Wyatt Professor of Drug Discovery and Head of the Drug Discovery Unit
The discovery of therapeutics for neglected diseases and the translation of novel biology through small molecule drug discovery 		BCDD
Joost Zomerdijk Reader in Gene Regulation and Expression
Molecular mechanisms and control in transcription by RNA polymerase I 		GRE