Head of Division: Alan Fairlamb
Deputy Head of Division: Ian Gilbert
Secretary:
Claire Kadoch, Kate Scott,
Lab Manager:
Shona McInroy , Brian Weryk
The overarching theme of the Division is "the discovery of chemical solutions to biological problems" through excellence in basic and applied multidisciplinary research. Discovery, characterization and validation of drug targets in neglected diseases such as trypanosomiasis, leishmaniasis, malaria and other bacterial pathogens is a major research focus. Knowledge gained from these fundamental studies forms the foundation for translation into novel drug-like leads through a combination of high throughput screening, structure based design and medicinal chemistry. We also have an interest in discovering small molecules that influence stem cell fate in order to develop specific cell types for drug discovery. To meet these challenges in basic and translational research, members of the Division include specialists in bioinformatics, enzymology, molecular biology, glycobiology, in vitro and in vivo pharmacology and synthetic organic and medicinal chemistry.
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Geoff Barton Professor of Bioinformatics Protein and nucleic acid sequence analysis and functional predictions |
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Ruth Brenk Lecturer in Computational Chemistry Developing and applying computational methods to predict the interactions of small molecules with macromolecules. |
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Alan Fairlamb Professor of Biochemistry, Wellcome Principal Research Fellow and Head of the Division of Biological Chemistry and Drug Discovery |
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Mike Ferguson Professor of Molecular Parasitology and Dean of Research Molecular parasitology, glycobiology and drug discovery |
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Ian Gilbert Professor of Medicinal Chemistry and Deputy-Head of the Division of Biological Chemistry and Drug Discovery Design and synthesis of potential therapeutic agents |
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David Gray Head of Biology Molecular Pharmacology and Compound Screening |
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Andrew Hopkins Professor of Medicinal Informatics and SULSA Research Professor of Translational Biology Chemoinformatics, chemogenomics and drug discovery |
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Bill Hunter Professor of Structural Biology Protein structure and function; fundamental chemical biology and early stage antimicrobial drug discovery |
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Andrei Nikolaev Reader in Organic Chemistry The chemical synthesis of complex phosphosaccharides |
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Kevin Read Head of DMPK for the Drug Discovery Unit Distribution, metabolism and pharmacokinetics of drugs |
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Paul Wyatt Professor of Drug Discovery and Head of the Drug Discovery Unit The discovery of therapeutics for neglected diseases and the translation of novel biology through small molecule drug discovery |
