University of Dundee

Biological Chemistry

Mechanisms of intracellular transport in trypanosomes

A project to study the molecular mechanisms, functions and evolution of membrane transport in the African trypanosome is offered in the laboratory of Prof Mark Field. The work will investigate in detail the roles of a family of proteins recently identified as interacting with clathrin, the major endocytic coat protein, and which appear to be features specific to trypanosomes. Data will have relevance to parasitology, molecular evolution and the search for therapeutic targets. The project will involve state of the art proteomics, high resolution imaging and genetics/molecular biology.