University of Dundee

Dr Catharine Goddard

Position: 
Manager, Wellcome Centre for Anti-Infectives Research
Address: 
School of Life Sciences
Full Telephone: 
+44 (0) 1382 383457, int ext 83457
Email: 

Biography

As Manger for the Wellcome Centre for Anti-Infectives Research Catharine oversees the operations, finance and communication for the Centre. She works closely with the Director and senior management team to set the strategy for the Centre across its research, training and public engagement themes.

Catharine joins the Wellcome Centre for Anti-Infectives Research from her position as Manager of The Farr Institute for Health Informatics Research. The Farr Institute was a UK-wide research collaboration involving 21 academic institutions and health partners in England, Scotland and Wales. Publically funded by a consortium of ten organisations led by the Medical Research Council, the Institute was committed to delivering high-quality, cutting-edge research using ‘big data’ to advance the health and care of patients and the public. Catharine directed the operational strategy with responsibility for the Network budget and for facilitating and implementing interactions across The Farr Institute and between The Farr Institute and the wider UK health informatics research community. Catharine worked closely with each of the four Farr Institute Centres and the leads of the eight UK Network working groups to ensure effective coordination of activities to meet strategic objectives.

From 2010-2014 Catharine was University of Dundee programme manager for the Kuwait-Scotland eHealth Innovation Network (KSeHIN). KSeHIN is an international collaboration involving the University of Dundee, NHS Tayside and Aridhia Informatics from Scotland and the Dasman Diabetes Institute and Ministry of Health in Kuwait. The aim of KSeHIN is to enhance care and management of people with diabetes through the application of relevant and appropriate evidence based processes, skills and knowledge. The collaboration has created a University of Dundee accredited Masters programme, built a National Clinical Skills and Simulation centre in Kuwait and introduced a shared electronic patient record linking primary and secondary healthcare for the first time in Kuwait.

Catharine was responsible for ensuring the integration of projects across the four work-streams of Education, Informatics, Research and Clinical Services. Catharine also acted as the project manager for the Education team responsible for coordinating and implementing the delivery of the Education programme to the students in Kuwait.

From 2006-2010 Catharine worked for Wyeth/Pfizer where she managed biomarker research as part of the Translational Medicine team. Catharine implemented biomarker strategies with both clinical and pre-clinical drug discovery teams. Catharine was a senior member of the Translational Medicine Research Collaboration (TMRC) between Wyeth and the Scottish Universities and NHS, managing the portfolio of Cardiovascular and Diabetes research projects and acting as project manager for a research collaboration to identify novel biomarkers predictive of drug toxicity.

Catharine started her research career at the University of Cambridge where she specialised in using genetically modified mice to further understand the molecular and cellular lesions underlying human diseases, including cardiac arrhythmias and Cystic Fibrosis.

Publications

Selected Publications

Aitken M,  Tully MP, Porteous C, Denegri S et al 'Consensus Statement on Public Involvement and Engagement with Data-Intensive Health Research' International Journal Population Data Science  DOI https://doi.org/10.23889/ijpds.v4i1.586

Wake DJ, Sukkar F, Goddard C, Halawa N, Barake R, Chisholm S, Morris A, Behbehani K, Ker J, Scott M. ‘Transformation of diabetes care in Kuwait through postgraduate healthcare professional education’ Diabetic Medicine 2014,31:112

Conway NT et al ‘The Kuwait-Scotland eHealth Innovation Network (KSeHIN): a sustainable approach to quality improvement in healthcare.’ Quality in Primary Care 2014; 22:43-51

Burch LR, Zhou K, Donnelly LA, Doney ASF, Brady J, Goddard CA, Morris AD, Hansen MK, Palmer CNA  'A single nucleotide polymorphism on exon-4 of the gene encoding PPARδ is associated with reduced height in adults and children'  J Clin Endocrinol Metab 2009, 94(7), 2587-2593

Feuerstein GZ, Wan HI, Walsh F, Goddard C, Parsons S, Coughlin CM, Rutkowski L, Alesci S, Lee JH, Koening W, Smith M. 'Translational Medicine Perspectives in Drug Discovery and Development-Part IV: “Surrogate Diseases” Pave the Way for Successful Proof-of-Concept Studies Towards Investment Decisions in Large Morbidity and Mortality Outcome Studies in Major Diseases.’ American Drug Discovery 2008, 3, 26-32

Goddard CA, Ghais N, Zhang Y, Williams AJ, Colledge WH, Grace AA, Huang CL. ‘Physiological consequences of the P2328S mutation in the ryanodine receptor (RyR2) gene in genetically modified murine hearts.’ Acta Physiol (Oxf). 2008, 194:123-40

Gill DR, SE Smyth, CA Goddard, IA Pringle, CF Higgins, WH Colledge, SC Hyde ‘Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor1 promoter’ Gene Therapy 2001, 8: 1539-1546

Goddard CA, MJ Evans, WH Colledge 'Genistein activates CFTR-mediated Cl- secretion in the murine trachea and colon.' American Journal of Physiology, Cell Physiology 2000, 279: C383-C392

Goddard CA, R Ratcliffe, JR Anderson, E Glenn, S Brown, DR Gill, SC Hyde, LJ MacVinish, L Huang, CF Higgins, AW Cuthbert, MJ Evans and WH Colledge. ‘A second dose of a CFTRcDNA/liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea.' Gene Therapy 1997, 4:1231-1236

MacVinish LJ, CA Goddard WH Colledge, CF Higgins, MJ Evans and AW Cuthbert. 'Normalisation of ion transport in murine cystic fibrosis nasal epithelium using gene transfer.' American Journal of Physiology 1997, 273: C734-C740