11 Nov 2015
The MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) is pleased to share a new video that describes one of the most significant components of the research carried out in the Unit – communication between cells. Entitled ‘The Heart of Research and Discovery’ and narrated by the stage and film actor Brian Cox, the animation conveys the significance of signalling events and explains how this is mediated by phosphorylation.
12 Aug 2015
A stage-by-stage picture of a key cellular mechanism associated with the development of Parkinson’s Disease has been captured for the first time by a research team led by the University of Dundee. The findings give further understanding of the possible causes of Parkinson’s disease and offer potential for multiple targets for therapeutics to be developed.
11 Jun 2015
Two Ph.D. students from Life Sciences at the University of Dundee have been invited to the highly prestigious Roche Continents - a full week of interdisciplinary challenges and inspiration at Roche Continents which takes place in Salzburg (during the Salzburg Festival) from August 11-17.
15 Apr 2015
The deubiquitylase OTUB1 is ubiquitously expressed and is known to impact key cellular processes, from TGFβ and p53 signalling to DNA damage repair, by targeting a multitude of substrates both in the cytoplasm and nucleus. Until now it was not known how OTUB1 navigated around the subcellular compartments.
12 Dec 2014
This week The Courier ran its Impact 100 list of the most influential individuals and organisations from across Tayside and Fife in 2014. The University of Dundee is strongly represented in the poll, with 17 placings and listings for staff, students, graduates, honorary graduates and other friends of the University below. Two of the most prominent members of the College of Life Sciences, Professor Sir Philip Cohen and Professor Mike Ferguson feature on the list as well as long-time CLS associate Professor Sue Black of CAHID.
31 Oct 2014
Scientists at the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) at the University of Dundee have solved an important part of the mystery about one of the most fundamental processes in cell biology.
22 Oct 2014
Ubiquigent Limited, a company specialising in ubiquitin cell-signalling system drug discovery capabilities and services, and the Drug Discovery Unit (the DDU) of the University of Dundee, announced today they have entered into a collaboration agreement to develop and market new ubiquitin system targeted compound libraries aimed at discovering potent and selective therapeutics across multiple areas including; cancer, cardiovascular and metabolic, neurological and musculoskeletal, and infection and immunity.
02 Oct 2014
Dr Victoria Cowling, of the College of Life Sciences at the University of Dundee, has been awarded the inaugural Women in Cell Biology Early Career Award Medal by the British Society for Cell Biology. The Medal has been established to mark the 50th anniversary of the founding of the BSCB. It will be an annual honour awarded to an outstanding female cell biologist who has started their own research group in the UK within the last seven years.
27 Aug 2014
The potential to develop new drugs to target a class of enzymes implicated in major diseases such as cancer and neurodegenerative conditions has been boosted with the development of a new drug discovery method in a research effort led by the University of Dundee. The research group have been examining the class of enzymes called deubiquitylases (DUBs). Around 90 DUBs have been identified in the human genome and they are active in almost every process in cells.
10 Jul 2014
New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated. The discovery answers a key question about one of the most widely-researched proteins in human biology, which has been the subject of tens of thousands of research papers and millions of pounds in research funding.